Polymerization of actin filaments against membranes produces force for numerous cellular
processes, such as migration, morphogenesis, endocytosis, phagocytosis and organelle …

Cellular actin networks exhibit a wide range of sizes, shapes, and architectures tailored to
their biological roles. Once assembled, these filamentous networks are either maintained in …

When the non-coding repeat expansion in the C9ORF72 gene was discovered to be the
most frequent cause of frontotemporal dementia (FTD) and amyotrophic lateral sclerosis …

The actin cytoskeleton undergoes extensive remodeling during cell morphogenesis and
motility. The small guanosine triphosphatase Rho regulates such remodeling, but the …

▪ Abstract We review how motile cells regulate actin filament assembly at their leading edge.
Activation of cell surface receptors generates signals (including activated Rho family …

Cell division, cell motility and the formation and maintenance of specialized structures in
differentiated cells depend directly on the regulated dynamics of the actin cytoskeleton,. To …

Proteins of the actin depolymerizing factor (ADF)/cofilin family are ubiquitous among
eukaryotes and are essential regulators of actin dynamics and function. Mammalian neurons …

Cell Movements vividly describes how complex movements can arise from the properties
and behaviors of biological molecules. This second edition is updated throughout with …

▪ Abstract Ubiquitous among eukaryotes, the ADF/cofilins are essential proteins responsible
for the high turnover rates of actin filaments in vivo. In vertebrates, ADF and cofilin are …

The plasma membrane and the underlying cortical actin cytoskeleton undergo continuous
dynamic interplay that is responsible for many essential aspects of cell physiology …