Multiplexed imaging in oncology
In oncology, technologies for clinical molecular imaging are used to diagnose patients,
establish the efficacy of treatments and monitor the recurrence of disease. Multiplexed …
establish the efficacy of treatments and monitor the recurrence of disease. Multiplexed …
Current trends in cancer nanotheranostics: metallic, polymeric, and lipid-based systems
Theranostics has emerged in recent years to provide an efficient and safer alternative in
cancer management. This review presents an updated description of nanotheranostic …
cancer management. This review presents an updated description of nanotheranostic …
[HTML][HTML] Enhancing RNA-lipid nanoparticle delivery: organ-and cell-specificity and barcoding strategies
PS Wei, N Thota, G John, E Chang, S Lee… - Journal of Controlled …, 2024 - Elsevier
Recent advancements in RNA therapeutics highlight the critical need for precision gene
delivery systems that target specific organs and cells. Lipid nanoparticles (LNPs) have …
delivery systems that target specific organs and cells. Lipid nanoparticles (LNPs) have …
Multifunctional polymeric micellar nanomedicine in the diagnosis and treatment of cancer
Polymeric micelles are a prevalent topic of research for the past decade, especially
concerning their fitting ability to deliver drug and diagnostic agents. This delivery system …
concerning their fitting ability to deliver drug and diagnostic agents. This delivery system …
Multifunctional polysaccharide nanoprobes for biological imaging
J Ju, D Xu, X Mo, J Miao, L Xu, G Ge, X Zhu… - Carbohydrate …, 2023 - Elsevier
Imaging and tracking biological targets or processes play an important role in revealing
molecular mechanisms and disease states. Bioimaging via optical, nuclear, or magnetic …
molecular mechanisms and disease states. Bioimaging via optical, nuclear, or magnetic …
Recent progresses in the development of hyaluronic acid-based nanosystems for tumor-targeted drug delivery and cancer imaging
HJ Cho - Journal of pharmaceutical investigation, 2020 - Springer
Background Hyaluronic acid (HA) has been widely used as one of major components of
nanocarriers for cancer imaging and therapy. HA possesses hydrophilic and anionic …
nanocarriers for cancer imaging and therapy. HA possesses hydrophilic and anionic …
68Ga-THP-PSMA: a PET imaging agent for prostate cancer offering rapid, room-temperature, 1-step kit-based radiolabeling
The clinical impact and accessibility of 68Ga tracers for the prostate-specific membrane
antigen (PSMA) and other targets would be greatly enhanced by the availability of a simple …
antigen (PSMA) and other targets would be greatly enhanced by the availability of a simple …
A hyaluronic acid conjugate engineered to synergistically and sequentially deliver gemcitabine and doxorubicin to treat triple negative breast cancer
Combination chemotherapy is commonly used to treat advanced breast cancer. However,
treatment success is often limited due to systemic toxicity. To improve therapeutic efficacy …
treatment success is often limited due to systemic toxicity. To improve therapeutic efficacy …
Polymer-drug conjugates as nanotheranostic agents
S Manandhar, E Sjöholm, J Bobacka… - Journal of …, 2021 - mdpi.com
Since the last decade, the polymer-drug conjugate (PDC) approach has emerged as one of
the most promising drug-delivery technologies owing to several benefits like circumventing …
the most promising drug-delivery technologies owing to several benefits like circumventing …
Design of bio-responsive hyaluronic acid–doxorubicin conjugates for the local treatment of glioblastoma
A Malfanti, G Catania, Q Degros, M Wang, M Bausart… - Pharmaceutics, 2022 - mdpi.com
Glioblastoma is an unmet clinical need. Local treatment strategies offer advantages, such as
the possibility to bypass the blood–brain barrier, achieving high drug concentrations at the …
the possibility to bypass the blood–brain barrier, achieving high drug concentrations at the …