Human genetics has emerged as one of the most dynamic areas of biology, with a
broadening societal impact. In this review, we discuss recent achievements, ongoing efforts …

Population stratification (PS) is a primary consideration in studies of genetic determinants of
human traits. Failure to control for PS may lead to confounding, causing a study to fail for …

Latin America continues to be severely underrepresented in genomics research, and fine-
scale genetic histories and complex trait architectures remain hidden owing to insufficient …

The vast majority of genome-wide association studies (GWASs) are performed in
Europeans, and their transferability to other populations is dependent on many factors (eg …

Over the past 500 years, North America has been the site of ongoing mixing of Native
Americans, European settlers, and Africans (brought largely by the trans-Atlantic slave …

The 21st century marks the emergence of “big data” with a rapid increase in the availability
of datasets with multiple measurements. In neuroscience, brain-imaging datasets are more …

Abstract The Greater Middle East (GME) has been a central hub of human migration and
population admixture. The tradition of consanguinity, variably practiced in the Persian Gulf …

INTRODUCTION The consensus view on the peopling of the Americas is that ancestors of
modern Native Americans entered the Americas from Siberia via the Bering Land Bridge …

Mexico harbors great cultural and ethnic diversity, yet fine-scale patterns of human genome-
wide variation from this region remain largely uncharacterized. We studied genomic …

US Hispanic/Latino individuals are diverse in genetic ancestry, culture, and environmental
exposures. Here, we characterized and controlled for this diversity in genome-wide …