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Aspergillus fumigatus and Aspergillosis in 2019
JP Latgé, G Chamilos - Clinical microbiology reviews, 2019 - journals.asm.org
Aspergillus fumigatus is a saprotrophic fungus; its primary habitat is the soil. In its ecological
niche, the fungus has learned how to adapt and proliferate in hostile environments. This …
niche, the fungus has learned how to adapt and proliferate in hostile environments. This …
Aspergillus fumigatus morphology and dynamic host interactions
Aspergillus fumigatus is an environmental filamentous fungus that can cause life-threatening
disease in immunocompromised individuals. The interactions between A. fumigatus and the …
disease in immunocompromised individuals. The interactions between A. fumigatus and the …
Defining physiological normoxia for improved translation of cell physiology to animal models and humans
TP Keeley, GE Mann - Physiological reviews, 2019 - journals.physiology.org
The extensive oxygen gradient between the air we breathe (Po2~ 21 kPa) and its ultimate
distribution within mitochondria (as low as~ 0.5–1 kPa) is testament to the efforts expended …
distribution within mitochondria (as low as~ 0.5–1 kPa) is testament to the efforts expended …
Pathogenicity and virulence of Aspergillus fumigatus
Pulmonary infections caused by the mould pathogen Aspergillus fumigatus are a major
cause of morbidity and mortality globally. Compromised lung defences arising from …
cause of morbidity and mortality globally. Compromised lung defences arising from …
Aspergillus fumigatus and aspergillosis: from basics to clinics
The airborne fungus Aspergillus fumigatus poses a serious health threat to humans by
causing numerous invasive infections and a notable mortality in humans, especially in …
causing numerous invasive infections and a notable mortality in humans, especially in …
New pathogens, new tricks: emerging, drug‐resistant fungal pathogens and future prospects for antifungal therapeutics
Fungal pathogens are a growing threat to public health. As human immunodeficiency
becomes increasingly common, fungal infections are becoming more prevalent. The use of …
becomes increasingly common, fungal infections are becoming more prevalent. The use of …
[HTML][HTML] Exploring the genomic diversity of black yeasts and relatives (Chaetothyriales, Ascomycota)
Abstract The order Chaetothyriales (Pezizomycotina, Ascomycetes) harbours obligatorily
melanised fungi and includes numerous etiologic agents of chromoblastomycosis …
melanised fungi and includes numerous etiologic agents of chromoblastomycosis …
Fungal biofilm architecture produces hypoxic microenvironments that drive antifungal resistance
Human fungal infections may fail to respond to contemporary antifungal therapies in vivo
despite in vitro fungal isolate drug susceptibility. Such a discrepancy between in vitro …
despite in vitro fungal isolate drug susceptibility. Such a discrepancy between in vitro …
Antifungal therapy: Novel drug delivery strategies driven by new targets
S Wu, R Song, T Liu, C Li - Advanced Drug Delivery Reviews, 2023 - Elsevier
In patients with compromised immunity, invasive fungal infections represent a significant
cause of mortality. Given the limited availability and drawbacks of existing first-line antifungal …
cause of mortality. Given the limited availability and drawbacks of existing first-line antifungal …
ChIP-seq and In Vivo Transcriptome Analyses of the Aspergillus fumigatus SREBP SrbA Reveals a New Regulator of the Fungal Hypoxia Response and Virulence
The Aspergillus fumigatus sterol regulatory element binding protein (SREBP) SrbA belongs
to the basic Helix-Loop-Helix (bHLH) family of transcription factors and is crucial for …
to the basic Helix-Loop-Helix (bHLH) family of transcription factors and is crucial for …