The red edge: bilin-binding photoreceptors as optogenetic tools and fluorescence reporters
This review adds the bilin-binding phytochromes to the Chemical Reviews thematic issue
“Optogenetics and Photopharmacology”. The work is structured into two parts. We first …
“Optogenetics and Photopharmacology”. The work is structured into two parts. We first …
Red light optogenetics in neuroscience
Optogenetics, a field concentrating on controlling cellular functions by means of light-
activated proteins, has shown tremendous potential in neuroscience. It possesses superior …
activated proteins, has shown tremendous potential in neuroscience. It possesses superior …
Light-regulated gene expression in Bacteria: Fundamentals, advances, and perspectives
Numerous photoreceptors and genetic circuits emerged over the past two decades and now
enable the light-dependent ie, optogenetic, regulation of gene expression in bacteria …
enable the light-dependent ie, optogenetic, regulation of gene expression in bacteria …
Individual and shared digital repertoires–older adults managing digital services
R Hänninen, L Pajula, V Korpela… - … Communication & Society, 2023 - Taylor & Francis
The rise of public and other non-recreational digital services is based on the idea of catering
to the daily needs of the citizens cost-efficiently and with ease. Previous research has …
to the daily needs of the citizens cost-efficiently and with ease. Previous research has …
Optical approaches for investigating neuromodulation and G protein–coupled receptor signaling
Despite the fact that roughly 40% of all US Food and Drug Administration (FDA)-approved
pharmacological therapeutics target G protein–coupled receptors (GPCRs), there remains a …
pharmacological therapeutics target G protein–coupled receptors (GPCRs), there remains a …
Comparative analysis of two paradigm bacteriophytochromes reveals opposite functionalities in two-component signaling
E Multamäki, R Nanekar, D Morozov… - Nature …, 2021 - nature.com
Bacterial phytochrome photoreceptors usually belong to two-component signaling systems
which transmit environmental stimuli to a response regulator through a histidine kinase …
which transmit environmental stimuli to a response regulator through a histidine kinase …
Signal transduction in photoreceptor histidine kinases
A Möglich - Protein science, 2019 - Wiley Online Library
Two‐component systems (TCS) constitute the predominant means by which prokaryotes
read out and adapt to their environment. Canonical TCSs comprise a sensor histidine kinase …
read out and adapt to their environment. Canonical TCSs comprise a sensor histidine kinase …
Engineering bacteriophytochrome-coupled photoactivated adenylyl cyclases for enhanced optogenetic camp modulation
Sensory photoreceptors abound in nature and enable organisms to adapt behavior,
development, and physiology to environmental light. In optogenetics, photoreceptors allow …
development, and physiology to environmental light. In optogenetics, photoreceptors allow …
Nanobody-directed targeting of optogenetic tools to study signaling in the primary cilium
JN Hansen, F Kaiser, C Klausen, B Stüven, R Chong… - Elife, 2020 - elifesciences.org
Compartmentalization of cellular signaling forms the molecular basis of cellular behavior.
The primary cilium constitutes a subcellular compartment that orchestrates signal …
The primary cilium constitutes a subcellular compartment that orchestrates signal …
Engineering signalling pathways in mammalian cells
In mammalian cells, signalling pathways orchestrate cellular growth, differentiation and
survival, as well as many other processes that are essential for the proper functioning of …
survival, as well as many other processes that are essential for the proper functioning of …