[HTML][HTML] Sensitive periods of substance abuse: Early risk for the transition to dependence

CJ Jordan, SL Andersen - Developmental cognitive neuroscience, 2017 - Elsevier
Early adolescent substance use dramatically increases the risk of lifelong substance use
disorder (SUD). An adolescent sensitive period evolved to allow the development of risk …

Effect of stimulants on height and weight: a review of the literature

SV Faraone, J Biederman, CP Morley… - Journal of the American …, 2008 - Elsevier
OBJECTIVE: Stimulant medications are effective treatments for attention-deficit/hyperactivity
disorder, but concerns remain about their effects on growth. METHOD: We provide a …

Epigenetic side-effects of common pharmaceuticals: a potential new field in medicine and pharmacology

AB Csoka, M Szyf - Medical hypotheses, 2009 - Elsevier
The term “Epigenetics” refers to DNA and chromatin modifications that persist from one cell
division to the next, despite a lack of change in the underlying DNA sequence. The …

Postsynaptic ProSAP/Shank scaffolds in the cross-hair of synaptopathies

AM Grabrucker, MJ Schmeisser, M Schoen… - Trends in cell …, 2011 - cell.com
Intact synaptic homeostasis is a fundamental prerequisite for a healthy brain. Thus, it is not
surprising that altered synaptic morphology and function are involved in the molecular …

Integrated genome-wide association study findings: identification of a neurodevelopmental network for attention deficit hyperactivity disorder

G Poelmans, DL Pauls, JK Buitelaar… - American Journal of …, 2011 - psychiatryonline.org
Objective: Attention deficit hyperactivity disorder (ADHD) is a highly heritable
neuropsychiatric disorder. In the present study, the authors investigated the presence of …

Effect of antidepressant medications on semen parameters and male fertility

LA Beeder, MK Samplaski - International Journal of Urology, 2020 - Wiley Online Library
Antidepressant medications are commonly used in males of reproductive age for long‐term
treatment of depression, as well as other disorders. Although antidepressants are known to …

Neurobehavioral adaptations to methylphenidate: the issue of early adolescent exposure

EM Marco, W Adriani, LA Ruocco, R Canese… - Neuroscience & …, 2011 - Elsevier
Exposure to psychostimulants, including both abused and therapeutic drugs, can occur first
during human adolescence. Animal modeling is useful not only to reproduce adolescent …

Molecular genetics of addiction and related heritable phenotypes: genome‐wide association approaches identify “connectivity constellation” and drug target genes …

GR Uhl, T Drgon, C Johnson, CY Li… - Annals of the New …, 2008 - Wiley Online Library
Genome‐wide association (GWA) can elucidate molecular genetic bases for human
individual differences in complex phenotypes that include vulnerability to addiction. Here …

The Homer1 family of proteins at the crossroad of dopamine-glutamate signaling: An emerging molecular “Lego” in the pathophysiology of psychiatric disorders. A …

A de Bartolomeis, A Barone, EF Buonaguro… - Neuroscience & …, 2022 - Elsevier
Once considered only scaffolding proteins at glutamatergic postsynaptic density (PSD),
Homer1 proteins are increasingly emerging as multimodal adaptors that integrate different …

[HTML][HTML] ADHD and maturation of brain white matter: A DTI study in medication naive children and adults

C Bouziane, MWA Caan, HGH Tamminga… - NeuroImage: Clinical, 2018 - Elsevier
Several diffusion tensor imaging (DTI) studies in attention deficit hyperactivity disorder
(ADHD) have shown a delay in brain white matter (WM) development. Because these …