Therapeutic targeting of inflammation in hypertension: from novel mechanisms to translational perspective

EC Murray, R Nosalski, N MacRitchie… - Cardiovascular …, 2021 - academic.oup.com
Both animal models and human observational and genetic studies have shown that immune
and inflammatory mechanisms play a key role in hypertension and its complications. We …

Cardiovascular effects of approved drugs for rheumatoid arthritis

F Atzeni, J Rodríguez-Carrio, CD Popa… - Nature Reviews …, 2021 - nature.com
The risk of cardiovascular disease is increased in patients with rheumatoid arthritis
compared with the general population owing to the influence of traditional and non …

Non-coding RNAs in rheumatoid arthritis: from bench to bedside

J Wang, S Yan, J Yang, H Lu, D Xu… - Frontiers in immunology, 2020 - frontiersin.org
Rheumatoid arthritis is a common systemic and autoimmune disease characterized by
symmetrical and inflammatory destruction of distal joints. Its primary pathological characters …

Retinol binding protein 4 primes the NLRP3 inflammasome by signaling through Toll-like receptors 2 and 4

PM Moraes-Vieira, MM Yore… - Proceedings of the …, 2020 - pnas.org
Adipose tissue (AT) inflammation contributes to systemic insulin resistance. In obesity and
type 2 diabetes (T2D), retinol binding protein 4 (RBP4), the major retinol carrier in serum, is …

Circular RNA expression profiles of peripheral blood mononuclear cells in rheumatoid arthritis patients, based on microarray chip technology

F Zheng, X Yu, J Huang, Y Dai - Molecular medicine …, 2017 - spandidos-publications.com
Rheumatoid arthritis (RA) is a systemic autoimmune disease characterized by chronic
synovial inflammation and finally leads to variable degrees of bone and cartilage erosion …

Effect of anti-rheumatic drugs on cardiovascular disease events in rheumatoid arthritis

Y Baoqi, M Dan, Z **ngxing, Z Xueqing… - Frontiers in …, 2022 - frontiersin.org
Rheumatoid arthritis (RA) is an autoimmune disease characterized by erosive arthritis,
which can involve multiple systems. Patients with RA may have a variety of comorbidities …

Cardiovascular risk assessment in rheumatoid arthritis: accelerated atherosclerosis, new biomarkers, and the effects of biological therapy

D Popescu, E Rezus, MC Badescu, N Dima… - Life, 2023 - mdpi.com
Rheumatoid arthritis (RA), one of the most common of the chronic inflammatory autoimmune
diseases (CIADs), is recognized as an independent cardiovascular risk factor. Traditional …

Risk of diabetes mellitus associated with disease-modifying antirheumatic drugs and statins in rheumatoid arthritis

G Ozen, S Pedro, ME Holmqvist, M Avery… - Annals of the rheumatic …, 2017 - Elsevier
Objective To investigate the rate of incident diabetes mellitus (DM) in patients with
rheumatoid arthritis (RA) and the impact of disease-modifying antirheumatic drug (DMARD) …

Anti-TNF-alpha agents and endothelial function in rheumatoid arthritis: a systematic review and meta-analysis

F Ursini, C Leporini, F Bene, S D'Angelo, D Mauro… - Scientific Reports, 2017 - nature.com
Rheumatoid arthritis (RA) has been associated with endothelial dysfunction, a
pathophysiological feature of atherosclerosis. Our aim was to determine whether TNF-α …

[PDF][PDF] Rapid beneficial effect of the IL-6 receptor blockade on insulin resistance and insulin sensitivity in non-diabetic patients with rheumatoid arthritis

S Castañeda, S Remuzgo-Martínez… - Clin Exp …, 2019 - wiredspace.wits.ac.za
Objective In patients with rheumatoid arthritis (RA), insulin resistance (IR), a component of
the metabolic syndrome, is closely linked to the systemic inflammation induced by …