Effects of common antiepileptic drugs on teleost fishes
Antiepileptic drugs (AEDs) are globally prescribed to treat epilepsy and many other
psychiatric disorders in humans. Their high consumption, low metabolic rate in the human …
psychiatric disorders in humans. Their high consumption, low metabolic rate in the human …
Occurrence of pharmaceutical and pesticide transformation products in freshwater: update on environmental levels, toxicological information and future challenges
Pharmaceuticals and pesticides are recognized micropollutants in freshwater systems. Their
ever-increasing frequency of detection, levels found and little information available about …
ever-increasing frequency of detection, levels found and little information available about …
[HTML][HTML] Establishment of a human cell-based in vitro battery to assess developmental neurotoxicity hazard of chemicals
J Blum, S Masjosthusmann, K Bartmann, F Bendt… - Chemosphere, 2023 - Elsevier
Developmental neurotoxicity (DNT) is a major safety concern for all chemicals of the human
exposome. However, DNT data from animal studies are available for only a small …
exposome. However, DNT data from animal studies are available for only a small …
[HTML][HTML] Carbamazepine, venlafaxine, tramadol, and their main metabolites: Toxicological effects on zebrafish embryos and larvae
P Rodrigues, L Guimarães, AP Carvalho… - Journal of Hazardous …, 2023 - Elsevier
Pharmaceutical compounds and their metabolites are found in natural and wastewater.
However, investigation of their toxic effects on aquatic animals has been neglected …
However, investigation of their toxic effects on aquatic animals has been neglected …
Co-occurrence and spatial distribution of organic micropollutants in surface waters of the River Aconcagua and Maipo basins in Central Chile
Abstract Organic Micropollutants (OMPs) might pose significant risks to aquatic life and have
potential toxic effects on humans. These chemicals typically occur as complex mixtures …
potential toxic effects on humans. These chemicals typically occur as complex mixtures …
Cyclophosphamide alters the behaviors of adult Zebrafish via neurotransmitters and gut microbiota
Cyclophosphamide, one of the earliest prescribed alkylating anticancer drugs, has been
frequently detected in aquatic environments. However, its effects on fish behavior and …
frequently detected in aquatic environments. However, its effects on fish behavior and …
Temperature-and chemical-induced neurotoxicity in zebrafish
Throughout their lives, humans encounter a plethora of substances capable of inducing
neurotoxic effects, including drugs, heavy metals and pesticides. Neurotoxicity manifests …
neurotoxic effects, including drugs, heavy metals and pesticides. Neurotoxicity manifests …
High throughput sequencing of microRNA in rainbow trout plasma, mucus, and surrounding water following acute stress
Circulating plasma microRNAs (miRNAs) are well established as biomarkers of several
diseases in humans and have recently been used as indicators of environmental exposures …
diseases in humans and have recently been used as indicators of environmental exposures …
Differential molecular responses of zebrafish larvae to fluoxetine and norfluoxetine
P Rodrigues, V Cunha, M Ferreira, MA Reis-Henriques… - Water, 2022 - mdpi.com
The occurrence of psychopharmaceuticals in aquatic ecosystems is a growing problem.
Fluoxetine (FL) and its metabolite norfluoxetine (NF) are selective serotonin reuptake …
Fluoxetine (FL) and its metabolite norfluoxetine (NF) are selective serotonin reuptake …
Effects of curcumin to counteract levodopa-induced toxicity in zebrafish
P Briñez-Gallego, DG da Costa Silva… - Journal of Toxicology …, 2023 - Taylor & Francis
Parkinson's disease (PD) is a neurodegenerative disorder characterized by motor
dysfunction due to the death of dopaminergic neurons in the substantia nigra pars …
dysfunction due to the death of dopaminergic neurons in the substantia nigra pars …