Characterization of phage evolution and phage resistance in drug-resistant Stenotrophomonas maltophilia

P Han, W Lin, H Fan, Y Tong - Journal of Virology, 2024 - journals.asm.org
Phage therapy has become a viable antimicrobial treatment as an alternative to antibiotic
treatment, with an increase in antibiotic resistance. Phage resistance is a major limitation in …

Characterization and Genomic Analysis of a Novel Drexlervirial Bacteriophage IME268 with Lytic Activity Against Klebsiella pneumoniae

A Nazir, C Qi, N Shi, X Gao, Q Feng… - Infection and drug …, 2022 - Taylor & Francis
Introduction Klebsiella pneumoniae, a multidrug resistant bacterium, that causes nosocomial
infections including septicemia, pneumonia etc. Bacteriophages are potential antimicrobial …

Efficacy in Galleria mellonella larvae and application potential assessment of a new bacteriophage BUCT700 extensively lyse Stenotrophomonas maltophilia

Y Li, M Pu, P Han, M Li, X An, L Song, H Fan… - Microbiology …, 2023 - journals.asm.org
In recent years, Stenotrophomonas maltophilia (S. maltophilia) has become an important
pathogen of clinically acquired infections accompanied by high pathogenicity and high …

[HTML][HTML] Lytic spectra of tailed bacteriophages: a systematic review and meta-analysis

IM Pchelin, AV Smolensky, DV Azarov, AE Goncharov - Viruses, 2024 - mdpi.com
As natural predators of bacteria, tailed bacteriophages can be used in biocontrol
applications, including antimicrobial therapy. Also, phage lysis is a detrimental factor in …

[HTML][HTML] StenM_174: A Novel Podophage That Infects a Wide Range of Stenotrophomonas spp. and Suggests a New Subfamily in the Family Autographiviridae

VV Morozova, VI Yakubovskij, IK Baykov, YN Kozlova… - Viruses, 2023 - mdpi.com
Stenotrophomonas maltophilia was discovered as a soil bacterium associated with the
rhizosphere. Later, S. maltophilia was found to be a multidrug-resistant hospital-associated …

Characterization and genomic analysis of a lytic Stenotrophomonas maltophilia short-tailed phage A1432 revealed a new genus of the family Mesyanzhinovviridae

S Li, M Xu, D Yang, M Yang, H Wu, X Li… - Frontiers in …, 2024 - frontiersin.org
Stenotrophomonas maltophilia (S. maltophilia) is an emerging opportunistic pathogen that
exhibits resistant to a majority of commonly used antibiotics. Phages have the potential to …

Characterization of the Bacteriophage BUCT603 and Therapeutic Potential Evaluation Against Drug-Resistant Stenotrophomonas maltophilia in a Mouse Model

P Han, W Zhang, M Pu, Y Li, L Song, X An… - Frontiers in …, 2022 - frontiersin.org
Stenotrophomonas maltophilia (S. maltophilia) is a common opportunistic pathogen that is
resistant to many antibiotics. Bacteriophages are considered to be an effective alternative to …

Characterization and genome analysis of a novel Stenotrophomonas maltophilia bacteriophage BUCT598 with extreme pH resistance

K Han, X He, H Fan, L Song, X An, M Li, Y Tong - Virus Research, 2022 - Elsevier
Stenotrophomonas maltophilia (S. maltophilia) is an important Gram-negative opportunistic
pathogen that is widely distributed in nature. S. maltophilia is highly drug-resistant because …

Isolation and genomic characterization of a novel Autographiviridae bacteriophage IME184 with lytic activity against Klebsiella pneumoniae

F Li, F Tian, A Nazir, S Sui, M Li, D Cheng, S Nong… - Virus Research, 2022 - Elsevier
Klebsiella pneumoniae, a multidrug resistant bacterium that causes nosocomial infections
including septicemia, pneumonia etc. Bacteriophages are potential antimicrobial agents for …

[HTML][HTML] Characterization of bacteriophage BUCT631 lytic for K1 Klebsiella pneumoniae and its therapeutic efficacy in Galleria mellonella larvae

P Han, M Pu, Y Li, H Fan, Y Tong - Virologica Sinica, 2023 - Elsevier
Severe infections caused by multidrug-resistant Klebsiella pneumoniae (K. pneumoniae)
highlight the need for new therapeutics with activity against this pathogen. Phage therapy is …