Sirtuins in macrophage immune metabolism: A novel target for cardiovascular disorders
C Xu, J Li, Z Liang, Y Zhong, Z Zhang, X Hu… - International Journal of …, 2024 - Elsevier
Abstract Sirtuins (SIRT1-SIRT7), as a family of NAD+-dependent protein modifying enzymes,
have various catalytic functions, such as deacetylases, dealkalylases, and deribonucleases …
have various catalytic functions, such as deacetylases, dealkalylases, and deribonucleases …
Drug discovery inspired by bioactive small molecules from nature
S Kim, SW Lim, J Choi - Animal Cells and Systems, 2022 - Taylor & Francis
Natural products (NPs) have greatly contributed to the development of novel treatments for
human diseases such as cancer, metabolic disorders, and infections. Compared to synthetic …
human diseases such as cancer, metabolic disorders, and infections. Compared to synthetic …
Investigating the Chemical Composition of Lepidium sativum Seeds and Their Ability to Safeguard against Monosodium Glutamate-Induced Hepatic Dysfunction
Monosodium glutamate (MSG) is one of the most frequently used food additives that
endanger public health. The antioxidant, hyperlipidemic, and cytoprotective properties of …
endanger public health. The antioxidant, hyperlipidemic, and cytoprotective properties of …
Isolation and pharmacochemistry of α-mangostin as a chemotherapeutic agent
MS Meah, P Panichayupakaranant… - Pharmacognosy …, 2024 - journals.sagepub.com
A naturally occurring xanthone, mangostanin (1, 3, 6-trihydroxy-7-methoxy-2, 8-bis (3-
methylbut-2-en-1-yl)-9 H-xanthen-9-one), was isolated from Garcinia mangostana L. It …
methylbut-2-en-1-yl)-9 H-xanthen-9-one), was isolated from Garcinia mangostana L. It …
Demethylcalabaxanthone from Garcinia mangostana Exerts Antioxidant Effects through the Activation of the Nrf2 Pathway as Assessed via Molecular Docking and …
Nuclear factor erythroid 2-related factor 2 (Nrf2) pathway activation promotes the expression
of antioxidant enzymes in response to rising oxidative stress, resulting in reactive oxygen …
of antioxidant enzymes in response to rising oxidative stress, resulting in reactive oxygen …
3-Demethyl-2-geranyl-4-prenylbellidifoline, a natural xanthone with diuretic and kidney protective properties
LNB Mariano, T Boeing, VC Filho… - Journal of Pharmacy …, 2024 - academic.oup.com
Objectives The diuretic and kidney protective effect of the 3-demethyl-2-geranyl-4-
prenylbellidifoline (DGP) were evaluated in rats. Methods The normotensive (NTR) and …
prenylbellidifoline (DGP) were evaluated in rats. Methods The normotensive (NTR) and …
α-Mangostin suppresses ethanol-induced gastric ulceration by regulating the Nrf2/HO-1 and NF-κB/NLRP3/caspase-1 signaling pathways and gut microbiota
Abstract α-Mangostin is a natural xanthone derivative isolated from Camellia atrophy (CA),
commonly known as Lichuan black tea (LBT). The present study investigated the …
commonly known as Lichuan black tea (LBT). The present study investigated the …
[HTML][HTML] Differential cytotoxic effects of Garcinia mangostana pericarp extract on leukaemic versus normal human cell lines: insights into selective anticancer activity
Introduction Garcinia mangostana L. is widely recognised for its traditional medicinal uses
and growing relevance in the nutraceutical sector. This research endeavour is designed to …
and growing relevance in the nutraceutical sector. This research endeavour is designed to …
Sitosterol-rich Digera muricata against 7-ketocholesterol and lipopolysaccharide-mediated atherogenic responses by modulating NF-ΚB/iNOS signalling pathway in …
S Ravi, P Duraisamy, M Krishnan, LC Martin… - 3 Biotech, 2023 - Springer
Digera muricata L., commonly known as Tartara, is an edible herb used as traditional
medicine in many countries of Africa and Asia. This study aimed to elucidate the effect of a …
medicine in many countries of Africa and Asia. This study aimed to elucidate the effect of a …
Updating the Pharmacological Effects of α-Mangostin Compound and Unraveling Its Mechanism of Action: A Computational Study Review
Abstract α-Mangostin, initially identified in 1855, is a xanthone derivative compound
predominantly located in the pericarp of the mangosteen fruit (Garcinia mangostana L). This …
predominantly located in the pericarp of the mangosteen fruit (Garcinia mangostana L). This …