[HTML][HTML] Organs-on-chips technologies–A guide from disease models to opportunities for drug development

AG Monteduro, S Rizzato, G Caragnano… - Biosensors and …, 2023 - Elsevier
Current in-vitro 2D cultures and animal models present severe limitations in recapitulating
human physiopathology with striking discrepancies in estimating drug efficacy and side …

Dielectric spectroscopy as a viable biosensing tool for cell and tissue characterization and analysis

K Heileman, J Daoud, M Tabrizian - Biosensors and Bioelectronics, 2013 - Elsevier
The use of dielectric spectroscopy to carry out real time observations of cells and to extract a
wealth of information about their physiological properties has expanded in recent years. This …

Micro total analysis systems: fundamental advances and applications in the laboratory, clinic, and field

ML Kovarik, DM Ornoff, AT Melvin, NC Dobes… - Analytical …, 2013 - ACS Publications
Assay devices designed for these applications offer improvements to existing methods or
provide fundamentally new strategies. Both mature methods and novel techniques have …

Recent advances in electrical impedance sensing technology for single-cell analysis

Z Zhang, X Huang, K Liu, T Lan, Z Wang, Z Zhu - Biosensors, 2021 - mdpi.com
Cellular heterogeneity is of significance in cell-based assays for life science, biomedicine
and clinical diagnostics. Electrical impedance sensing technology has become a powerful …

Biosensors for the detection of food pathogens

P Poltronieri, V Mezzolla, E Primiceri, G Maruccio - Foods, 2014 - mdpi.com
Food pathogens frequently cause foodborne diseases. There is a need to rapidly identify the
source of the bacteria in order to contain their spread and epidemics. A pre-enrichment …

Key enabling technologies for point-of-care diagnostics

E Primiceri, MS Chiriacò, FM Notarangelo, A Crocamo… - Sensors, 2018 - mdpi.com
A major trend in biomedical engineering is the development of reliable, self-contained point-
of-care (POC) devices for diagnostics and in-field assays. The new generation of such …

Fabrication of a label-free electrochemical cell-based biosensor for toxicity assessment of thiram

X Wei, C Liu, Z Li, Q Sun, X Zhang, Y Li, W Zhang, J Shi… - Chemosphere, 2022 - Elsevier
Thiram has been widely used in agriculture and may invades the food chain, posing a threat
to human health. In this research, a label-free electrochemical cell-based biosensor was …

Cell chips as new tools for cell biology–results, perspectives and opportunities

E Primiceri, MS Chiriaco, R Rinaldi, G Maruccio - Lab on a Chip, 2013 - pubs.rsc.org
Cell culture technologies were initially developed as research tools for studying cell
functions, but nowadays they are essential for the biotechnology industry, with rapidly …

[HTML][HTML] Microfabricated Electrochemical Cell-Based Biosensors for Analysis of Living Cells In Vitro

J Wang, C Wu, N Hu, J Zhou, L Du, P Wang - Biosensors, 2012 - mdpi.com
Cellular biochemical parameters can be used to reveal the physiological and functional
information of various cells. Due to demonstrated high accuracy and non-invasiveness …

Mesenchymal‐mode migration assay and antimetastatic drug screening with high‐throughput microfluidic channel networks

Y Zhang, W Zhang, L Qin - Angewandte Chemie, 2014 - Wiley Online Library
Increasing evidence shows that activated mesenchymal migration is a key process of the
metastatic cascade. Cancer cells usually gain such migratory capability through an epithelial …