Antimicrobial peptides (AMPs) have remarkably different structures as well as biological
activity profiles, whereupon most of these peptides are supposed to kill bacteria via …

The human cathelicidin hCAP18/LL-37 has become a paradigm for the pleiotropic roles of
peptides in host defence. It has a remarkably wide functional repertoire that includes direct …

Cathelicidins are a group of antimicrobial peptides. Since their discovery, it has become
clear that they are an exceptional class of peptides, with some members having pleiotropic …

Antimicrobial peptides (AMPs), as well as host defense peptides (HDPs), constitute the first
line of defense as part of the innate immune system. Humans are known to express …

Antimicrobial peptides serve as a first line of innate immune defense against invading
organisms such as bacteria and viruses. In this study, we hypothesized that peptides …

Diabetic patients often have ulcers on their lower-limbs that are infected by multiple biofilm-
forming genera of bacteria, and the elimination of the biofilm has proven highly successful in …

Antimicrobial peptides are a vital component of the innate immune system of all eukaryotic
organisms and many of these peptides have potent antifungal activity. They have potential …

As a key component of the innate immunity system, human cathelicidin LL-37 plays an
essential role in protecting humans against infectious diseases. To elucidate the structural …

The human cathelicidin LL-37 serves a critical role in the innate immune system defending
bacterial infections. LL-37 can interact with molecules of the cell wall and perforate …

Membrane proteins perform a host of vital cellular functions. Deciphering the molecular
mechanisms whereby they fulfill these functions requires detailed biophysical and structural …