This brief review explores the areas of cognitive impairment that have been observed in
cancer patients and survivors, the cognitive assessment tools used, and the management of …

Approximately 100,000 primary and metastatic brain tumor patients/year in the US survive
long enough (> 6 months) to experience radiation-induced brain injury. Prior to 1970, the …

PURPOSE Radiation dose to the neuroregenerative zone of the hippocampus has been
found to be associated with cognitive toxicity. Hippocampal avoidance (HA) using intensity …

PURPOSE Radiation dose received by the neural stem cells of the hippocampus during
whole-brain radiotherapy has been associated with neurocognitive decline. The key …

Purpose Hippocampal neural stem-cell injury during whole-brain radiotherapy (WBRT) may
play a role in memory decline. Intensity-modulated radiotherapy can be used to avoid …

Introduction To compare neurocognitive functioning in patients with SCLC who received
prophylactic cranial irradiation (PCI) with or without hippocampus avoidance (HA). Methods …

Background To determine if proton radiotherapy (PT), compared to intensity-modulated
radiotherapy (IMRT), delayed time to cognitive failure in patients with newly diagnosed …

Cell senescence is a driver of ageing, frailty, age-associated disease and functional decline.
In oncology, tumour cell senescence may contribute to the effect of adjuvant therapies, as it …

Dose constraints are essential for performing dosimetry, especially for intensity modulation
and for radiotherapy under stereotaxic conditions. We present the update of the …

Background: The safe use of radiotherapy (RT) requires compliance with dose/volume
constraints (DVCs) for organs at risk (OaRs). However, the available recommendations are …