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Targeting proliferating cell nuclear antigen (PCNA) as an effective strategy to inhibit tumor cell proliferation
M Cardano, C Tribioli, E Prosperi - Current cancer drug targets, 2020 - ingentaconnect.com
Targeting highly proliferating cells is an important issue for many types of aggressive tumors.
Proliferating Cell Nuclear Antigen (PCNA) is an essential protein that participates in a variety …
Proliferating Cell Nuclear Antigen (PCNA) is an essential protein that participates in a variety …
PCNA: a silent housekeeper or a potential therapeutic target?
SC Wang - Trends in pharmacological sciences, 2014 - cell.com
Proliferating cell nuclear antigen (PCNA) is known as a molecular marker for proliferation
given its role in replication. Three identical molecules of PCNA form a molecular sliding …
given its role in replication. Three identical molecules of PCNA form a molecular sliding …
A lesson for the maestro of the replication fork: targeting the protein‐binding interface of proliferating cell nuclear antigen for anticancer therapy
The proliferating cell nuclear antigen (PCNA) has emerged as a promising candidate for the
development of novel cancer therapeutics. PCNA is a nononcogenic mediator of DNA …
development of novel cancer therapeutics. PCNA is a nononcogenic mediator of DNA …
Tumor necrosis factor receptor 1 is a negative regulator of progenitor proliferation in adult hippocampal neurogenesis
Tumor necrosis factor-α (TNF-α) is a proinflammatory cytokine, acting through the TNF-R1
and TNF-R2 receptors. The two receptors have been proposed to mediate distinct TNF-α …
and TNF-R2 receptors. The two receptors have been proposed to mediate distinct TNF-α …
Myricitrin exhibits antioxidant, anti-inflammatory and antifibrotic activity in carbon tetrachloride-intoxicated mice
Abstract Myricetin-3-O-α-rhamnoside (myricitrin) is a naturally occurring phenolic compound
which possesses antioxidant and anti-inflammatory activity. The aim of this study was to …
which possesses antioxidant and anti-inflammatory activity. The aim of this study was to …
[HTML][HTML] The Role of n-3 Polyunsaturated Fatty Acids in the Prevention and Treatment of Breast Cancer
J Liu, DWL Ma - nutrients, 2014 - mdpi.com
Breast cancer (BC) is the most common cancer among women worldwide. Dietary fatty
acids, especially n-3 polyunsaturated fatty acids (PUFA), are believed to play a role in …
acids, especially n-3 polyunsaturated fatty acids (PUFA), are believed to play a role in …
[HTML][HTML] Salvadora persica attenuates DMBA-induced mammary cancer through downregulation oxidative stress, estrogen receptor expression and proliferation and …
Naturally occurring phytochemicals especially polyphenolic compounds have received
increasing attention as chemopreventive agents. The chemopreventive potential of the …
increasing attention as chemopreventive agents. The chemopreventive potential of the …
[PDF][PDF] The PCNA-RFC families of DNA clamps and clamp loaders
J Majka, PMJ Burgers - Progress in nucleic acid …, 2004 - burgerslab.biochem.wustl.edu
Progress in Nucleic Acid Research Copyright 2004, Elsevier Inc. and Molecular Biology, Vol.
78 227 All rights reserved. 0079-6603/04 $35.00 modeling. Its modification by ubiquitin …
78 227 All rights reserved. 0079-6603/04 $35.00 modeling. Its modification by ubiquitin …
Proteomics study reveals the molecular mechanisms underlying water stress tolerance induced by Piriformospora indica in barley
Piriformospora indica is a mutualistic root endophytic fungus, which transfers several
benefits to hosts including enhance plant growth and increase yield under both normal and …
benefits to hosts including enhance plant growth and increase yield under both normal and …
Potential of chemically modified hydrophilic surface characteristics to support tissue integration of titanium dental implants
F Schwarz, M Wieland, Z Schwartz… - … Research Part B …, 2009 - Wiley Online Library
In the past, several modifications of specific surface properties such as topography,
structure, chemistry, surface charge, and wettability have been investigated to predictably …
structure, chemistry, surface charge, and wettability have been investigated to predictably …