Advances in PET imaging of cancer

J Schwenck, D Sonanini, JM Cotton… - Nature Reviews …, 2023 - nature.com
Molecular imaging has experienced enormous advancements in the areas of imaging
technology, imaging probe and contrast development, and data quality, as well as machine …

Using PSMA imaging for prognostication in localized and advanced prostate cancer

MJ Roberts, T Maurer, M Perera, M Eiber… - Nature Reviews …, 2023 - nature.com
The use of prostate-specific membrane antigen (PSMA)-directed applications in modern
prostate cancer management has evolved rapidly over the past few years, hel** to …

[HTML][HTML] Management of patients with advanced prostate cancer—metastatic and/or castration-resistant prostate cancer: report of the Advanced Prostate Cancer …

S Gillessen, A Bossi, ID Davis, J de Bono… - European journal of …, 2023 - Elsevier
Background Innovations in imaging and molecular characterisation together with novel
treatment options have improved outcomes in advanced prostate cancer. However, we still …

[HTML][HTML] Castration-resistant prostate cancer: from uncovered resistance mechanisms to current treatments

TK Le, QH Duong, V Baylot, C Fargette, M Baboudjian… - Cancers, 2023 - mdpi.com
Simple Summary Castration-resistant prostate cancer (CRPC) remains a significant medical
challenge, even with recent advancements in diagnosis and treatment. To improve patient …

[177Lu] Lu-PSMA-617 plus enzalutamide in patients with metastatic castration-resistant prostate cancer (ENZA-p): an open-label, multicentre, randomised, phase 2 …

L Emmett, S Subramaniam, M Crumbaker… - The Lancet …, 2024 - thelancet.com
Summary Background Enzalutamide and lutetium-177 [177 Lu] Lu-prostate-specific
membrane antigen (PSMA)-617 both improve overall survival in patients with metastatic …

Reversible epigenetic alterations mediate PSMA expression heterogeneity in advanced metastatic prostate cancer

E Sayar, RA Patel, IM Coleman, MP Roudier… - JCI …, 2023 - pmc.ncbi.nlm.nih.gov
Prostate-specific membrane antigen (PSMA) is an important cell surface target in prostate
cancer. There are limited data on the heterogeneity of PSMA tissue expression in metastatic …

Theranostics and artificial intelligence: new frontiers in personalized medicine

GB Bilgin, C Bilgin, BJ Burkett, JJ Orme… - …, 2024 - pmc.ncbi.nlm.nih.gov
The field of theranostics is rapidly advancing, driven by the goals of enhancing patient care.
Recent breakthroughs in artificial intelligence (AI) and its innovative theranostic applications …

Status of PSMA-targeted radioligand therapy in prostate cancer: current data and future trials

A Jang, AT Kendi, O Sartor - Therapeutic Advances in …, 2023 - journals.sagepub.com
Metastatic prostate cancer continues to be an incurable disease. Despite all the novel
therapies approved in the past two decades, overall patient outcomes remain relatively poor …

Biological determinants of PSMA expression, regulation and heterogeneity in prostate cancer

MK Bakht, H Beltran - Nature Reviews Urology, 2025 - nature.com
Prostate-specific membrane antigen (PSMA) is an important cell-surface imaging biomarker
and therapeutic target in prostate cancer. The PSMA-targeted theranostic 177Lu-PSMA-617 …

Prostate-Specific Membrane Antigen–Targeted Therapies for Prostate Cancer: Towards Improving Therapeutic Outcomes

M Corpetti, C Müller, H Beltran, J de Bono… - European urology, 2024 - Elsevier
Context Prostate-specific membrane antigen (PSMA) is a transmembrane glycoprotein
overexpressed in most prostate cancers and exploited as a target for PSMA-targeted …