COVID-19 vaccine development: milestones, lessons and prospects

M Li, H Wang, L Tian, Z Pang, Q Yang… - Signal transduction and …, 2022 - nature.com
With the constantly mutating of SARS-CoV-2 and the emergence of Variants of Concern
(VOC), the implementation of vaccination is critically important. Existing SARS-CoV-2 …

Evaluation of the safety profile of COVID-19 vaccines: a rapid review

Q Wu, MZ Dudley, X Chen, X Bai, K Dong, T Zhuang… - BMC medicine, 2021 - Springer
Background The rapid process of research and development and lack of follow-up time post-
vaccination aroused great public concern about the safety profile of COVID-19 vaccine …

Immunological and clinical efficacy of COVID-19 vaccines in immunocompromised populations: a systematic review

S Galmiche, LBL Nguyen, E Tartour… - Clinical Microbiology …, 2022 - Elsevier
Background Available data show that COVID-19 vaccines may be less effective in
immunocompromised populations, who are at increased risk of severe COVID-19 …

The immune response to SARS-CoV-2 in people with HIV

MA Höft, WA Burgers, C Riou - Cellular & molecular immunology, 2024 - nature.com
This review examines the intersection of the HIV and SARS-CoV-2 pandemics. People with
HIV (PWH) are a heterogeneous group that differ in their degree of immune suppression …

The BNT162b2 mRNA vaccine elicits robust humoral and cellular immune responses in people living with human immunodeficiency virus (HIV)

BA Woldemeskel, AH Karaba, CC Garliss… - Clinical Infectious …, 2022 - academic.oup.com
Previous studies have shown that certain vaccines induce suboptimal responses in people
living with human immunodeficiency virus (HIV, PLWH). However, responses to severe …

Safety and immunogenicity of the ChAdOx1 nCoV-19 (AZD1222) vaccine against SARS-CoV-2 in people living with and without HIV in South Africa: an interim …

SA Madhi, AL Koen, A Izu, L Fairlie, CL Cutland… - The Lancet …, 2021 - thelancet.com
Background People living with HIV are at an increased risk of fatal outcome when admitted
to hospital for severe COVID-19 compared with HIV-negative individuals. We aimed to …

Humoral and cellular immune response elicited by mRNA vaccination against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in people living with …

A Antinori, S Cicalini, S Meschi… - Clinical Infectious …, 2022 - academic.oup.com
Abstract Background Data on SARS-CoV-2 vaccine immunogenicity in PLWH are currently
limited. Aim of the study was to investigate immunogenicity according to current CD4 T-cell …

COVID-19 outcomes and risk factors among people living with HIV

MA Spinelli, BLH Jones, M Gandhi - Current HIV/AIDS Reports, 2022 - Springer
Abstract Purpose of Review In this review, we examine the intersection of the HIV and
COVID-19 epidemics with focus on COVID-19-related health outcomes and risk factors for …

Influence of age on the effectiveness and duration of protection of Vaxzevria and CoronaVac vaccines: A population-based study

T Cerqueira-Silva, V de Araújo Oliveira… - The Lancet Regional …, 2022 - thelancet.com
Background Aging influences COVID-19 severity and response to vaccination, but previous
vaccine effectiveness (VE) analyzes lack the power to evaluate its role in subgroups within …

Humoral immune responses to COVID-19 vaccination in people living with HIV receiving suppressive antiretroviral therapy

ZL Brumme, F Mwimanzi, HR Lapointe, PK Cheung… - npj Vaccines, 2022 - nature.com
Humoral responses to COVID-19 vaccines in people living with HIV (PLWH) remain
incompletely characterized. We measured circulating antibodies against the SARS-CoV-2 …