Polymeric delivery of therapeutic nucleic acids
The advent of genome editing has transformed the therapeutic landscape for several
debilitating diseases, and the clinical outlook for gene therapeutics has never been more …
debilitating diseases, and the clinical outlook for gene therapeutics has never been more …
Poly (ethylene glycol) alternatives in biomedical applications
X Yao, C Qi, C Sun, F Huo, X Jiang - Nano Today, 2023 - Elsevier
Abstract Poly (ethylene glycol)(PEG) as gold standard has been extensively conjugated to
diagnostic and therapeutic agents or decorated on the surface of nanoplatforms, which is …
diagnostic and therapeutic agents or decorated on the surface of nanoplatforms, which is …
Hyaluronic acid for anticancer drug and nucleic acid delivery
Hyaluronic acid (HA) is widely used in anticancer drug delivery, since it is biocompatible,
biodegradable, non-toxic, and non-immunogenic; moreover, HA receptors are …
biodegradable, non-toxic, and non-immunogenic; moreover, HA receptors are …
Hyaluronic acid-based nanocarriers for anticancer drug delivery
CP Fu, XY Cai, SL Chen, HW Yu, Y Fang, XC Feng… - Polymers, 2023 - mdpi.com
Hyaluronic acid (HA), a main component of the extracellular matrix, is widely utilized to
deliver anticancer drugs due to its biocompatibility, biodegradability, non-toxicity, non …
deliver anticancer drugs due to its biocompatibility, biodegradability, non-toxicity, non …
Hyaluronic acid-based biopharmaceutical delivery and tumor-targeted drug delivery system
G Huang, H Huang - Journal of Controlled Release, 2018 - Elsevier
Hyaluronic acid (HA) is a natural polysaccharide with good biocompatibility and
degradability. HA and its derivatives can be used as sustained-release carriers for drugs …
degradability. HA and its derivatives can be used as sustained-release carriers for drugs …
Folate receptor‐mediated delivery of Cas9 RNP for enhanced immune checkpoint disruption in cancer cells
Y Lin, U Wilk, J Pöhmerer, E Hörterer, M Höhn, X Luo… - Small, 2023 - Wiley Online Library
The clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR‐
associated protein 9 (Cas9) system offers great opportunities for the treatment of numerous …
associated protein 9 (Cas9) system offers great opportunities for the treatment of numerous …
Strategies to overcome the polycation dilemma in drug delivery
A Bernkop-Schnürch - Advanced drug delivery reviews, 2018 - Elsevier
Because of polycationic auxiliary agents such as chitosan, polyethyleneimine and cell
penetrating peptides as well as cationic lipids assembling to polycationic systems, drug …
penetrating peptides as well as cationic lipids assembling to polycationic systems, drug …
Bioinert, stealth or interactive: how surface chemistry of nanocarriers determines their fate in vivo
Nanocarriers (NCs) have emerged as powerful tools to improve drug solubility, to promote
drug transport across membranes, to protect their payload from premature degradation, and …
drug transport across membranes, to protect their payload from premature degradation, and …
CD44 targeting biocompatible and biodegradable hyaluronic acid cross-linked zein nanogels for curcumin delivery to cancer cells: In vitro and in vivo evaluation
In this study, we developed novel hyaluronic acid cross-linked zein nanogels (HA-Zein NGs)
to deliver the potential anticancer agent curcumin (CRC), a naturally occurring …
to deliver the potential anticancer agent curcumin (CRC), a naturally occurring …
Carbohydrate-based nanocarriers and their application to target macrophages and deliver antimicrobial agents
Many deadly infections are produced by microorganisms capable of sustained survival in
macrophages. This reduces exposure to chemadrotherapy, prevents immune detection, and …
macrophages. This reduces exposure to chemadrotherapy, prevents immune detection, and …