Enhancing X‐Ray Sensitization with Multifunctional Nanoparticles
J Liu, JY Wu, T Chen, B Yang, XP Liu, J **, Z Zhang… - Small, 2024 - Wiley Online Library
In the progression of X‐ray‐based radiotherapy for the treatment of cancer, the incorporation
of nanoparticles (NPs) has a transformative impact. This study investigates the potential of …
of nanoparticles (NPs) has a transformative impact. This study investigates the potential of …
A review of recent advances in the modeling of nanoparticle radiosensitization with the Geant4-DNA toolkit
A Taheri, MU Khandaker, F Moradi… - Radiation Physics and …, 2023 - Elsevier
Metallic nanoparticles are promising agents for increasing the effectiveness of radiation
therapy by making cells more sensitive to radiation. High atomic number nanoparticles …
therapy by making cells more sensitive to radiation. High atomic number nanoparticles …
Synergistic effect of ferroptosis‐inducing nanoparticles and x‐ray irradiation combination therapy
C Bae, R Hernández Millares, S Ryu, H Moon, D Kim… - Small, 2024 - Wiley Online Library
Ferroptosis, characterized by the induction of cell death via lipid peroxidation, has been
actively studied over the last few years and has shown the potential to improve the efficacy …
actively studied over the last few years and has shown the potential to improve the efficacy …
Accessing radiation damage to biomolecules on the nanoscale by particle-scattering simulations
MB Hahn - Journal of Physics Communications, 2023 - iopscience.iop.org
Radiation damage to DNA plays a central role in radiation therapy to cure cancer. The
physico-chemical and biological processes involved encompass huge time and spatial …
physico-chemical and biological processes involved encompass huge time and spatial …
Dynamics of intracellular clusters of nanoparticles
Background Nanoparticles play a crucial role in nanodiagnostics, radiation therapy of
cancer, and they are now widely used to effectively deliver drugs to specific sites, targeting …
cancer, and they are now widely used to effectively deliver drugs to specific sites, targeting …
A method to implement inter-track interactions in Monte Carlo simulations with TOPAS-nBio and their influence on simulated radical yields following water radiolysis
L Derksen, V Flatten… - Physics in Medicine …, 2023 - iopscience.iop.org
Objective. In FLASH radiotherapy (dose rates≥ 40 Gy s− 1), a reduced normal tissue toxicity
has been observed, while maintaining the same tumor control compared to conventional …
has been observed, while maintaining the same tumor control compared to conventional …
A simulation study on the radiosensitization properties of gold nanorods
A Taheri, MU Khandaker, F Moradi… - Physics in medicine & …, 2024 - iopscience.iop.org
Objective. Gold nanorods (GNRs) have emerged as versatile nanoparticles with unique
properties, holding promise in various modalities of cancer treatment through drug delivery …
properties, holding promise in various modalities of cancer treatment through drug delivery …
Radial dependence of ionization clustering around a gold nanoparticle irradiated by X-rays under charged particle equilibrium
Objective. This work explores the enhancement of ionization clustering and its radial
dependence around a gold nanoparticle (NP), indicative of the induction of DNA lesions, a …
dependence around a gold nanoparticle (NP), indicative of the induction of DNA lesions, a …
Estimation of relative biological effectiveness of 225Ac compared to 177Lu during [225Ac]Ac-PSMA and [177Lu]Lu-PSMA radiopharmaceutical therapy using …
M Rumiantcev, WB Li, S Lindner, G Liubchenko… - EJNMMI physics, 2023 - Springer
Abstract Aim Over recent years,[225Ac] Ac-PSMA and [177Lu] Lu-PSMA
radiopharmaceutical therapy have evolved as a promising treatment option for advanced …
radiopharmaceutical therapy have evolved as a promising treatment option for advanced …
Application of high-z gold nanoparticles in targeted cancer radiotherapy—Pharmacokinetic modeling, monte carlo simulation and radiobiological effect modeling
Simple Summary High-Z gold nanoparticles show potential as radiosensitizers in the
radiotherapy of cancer. In this paper, we introduce the benefits and procedures for the …
radiotherapy of cancer. In this paper, we introduce the benefits and procedures for the …