Application of biomaterials in treating early osteonecrosis of the femoral head: Research progress and future perspectives

H Quan, C Ren, Y He, F Wang, S Dong, H Jiang - Acta biomaterialia, 2023 - Elsevier
Osteonecrosis of the femoral head (ONFH), a progressive pathological process of femoral
head ischemia and osteocyte necrosis, is a refractory orthopedic disease caused by multiple …

Icariin-loaded 3D-printed porous Ti6Al4V reconstruction rods for the treatment of necrotic femoral heads

H Lei, Z Zhou, L Liu, C Gao, Z Su, Z Tan, P Feng, M Liu… - Acta biomaterialia, 2023 - Elsevier
Avascular necrosis of the femoral head is a prevalent hip joint disease. Due to the damage
and destruction of the blood supply of the femoral head, the ischemic necrosis of bone cells …

Colon-targeted engineered postbiotics nanoparticles alleviate osteoporosis through the gut-bone axis

T Yu, R Bai, Z Wang, Y Qin, J Wang, Y Wei… - Nature …, 2024 - nature.com
The potential for mitigating intestinal inflammation through the gut-bone axis in the treatment
of osteoporosis is significant. While various gut-derived postbiotics or bacterial metabolites …

The polycaprolactone and silk fibroin nanofibers with Janus-structured sheaths for antibacterial and antioxidant by loading Taxifolin

K Jiao, M Sun, W Jia, Y Liu, S Wang, Y Yang, Z Dai… - Heliyon, 2024 - cell.com
Electrospinning is a widely recognized method for producing Janus or core-shell nanofibers.
In this study, nanofibrous membranes were fabricated through co-axial electrospinning …

[HTML][HTML] Hydrogel Use in Osteonecrosis of the Femoral Head

Z Bal, N Takakura - Gels, 2024 - mdpi.com
Osteonecrosis of the femoral head (ONFH) is a vascular disease of unknown etiology and
can be categorized mainly into two types: non-traumatic and traumatic ONFH. Thus …

Multifunctional Scaffold Comprising Metal–Organic Framework, Hydrogel, and Demineralized Bone Matrix for the Treatment of Steroid‐Induced Femoral Head …

L Bai, X Zhang, W Shen, P Wang, X Yin, J Liu, H Xu… - Small, 2025 - Wiley Online Library
Overproduction of reactive oxygen species (ROS) results in oxidative stress, a critical factor
in the pathogenesis of steroid‐induced osteonecrosis of the femoral head (SONFH). Excess …

[HTML][HTML] Human Umbilical Cord Mesenchymal Stem Cells Prevent Steroid-Induced Avascular Necrosis of the Femoral Head by Modulating Cellular Autophagy

C Zhong, H Xu, J Chen, W Cai, J Zhou, H Peng - Biomedicines, 2024 - mdpi.com
Background: Glucocorticoids (GCs) are critical regulatory molecules in the body, commonly
utilized in clinical practice for their potent anti-inflammatory and immunosuppressive …

Recent advances in nanomaterials for the treatment of femoral head necrosis

Y Yuan, M Zou, S Wu, C Liu, L Hao - Human Cell, 2024 - Springer
Osteonecrosis of the femoral head (ONFH) is a condition that causes considerable pain and
discomfort for patients, and its pathogenic mechanisms are not yet fully understood. While …

Cortistatin prevents glucocorticoid-associated osteonecrosis of the femoral head via the GHSR1a/Akt pathway

Y Gao, Y You, P Zhang, Y Yu, Z Xu, H Wei… - Communications …, 2024 - nature.com
Long-term use of glucocorticoids (GCs) is known to be a predominant cause of
osteonecrosis of the femoral head (ONFH). Moreover, GCs can mediate apoptosis of various …

[CITÁCIA][C] Minimally invasive treatment of early femoral head necrosis with β-tricalcium phosphate bioceramics.

X Wang, J Dai, W Fei, J Wang - Asian journal of surgery, 2024 - europepmc.org
Minimally invasive treatment of early femoral head necrosis with β-tricalcium phosphate
bioceramics. - Abstract - Europe PMC Sign in | Create an account https://orcid.org Europe PMC …