The potential for adaptive evolution to enable species persistence under a changing climate
is one of the most important questions for understanding impacts of future climate change …

Infectious diseases are among the strongest selective pressures driving human evolution,.
This includes the single greatest mortality event in recorded history, the first outbreak of the …

The unprecedented rate of extinction calls for efficient use of genetics to help conserve
biodiversity. Several recent genomic and simulation-based studies have argued that the …

The SLiM software framework for genetically explicit forward simulation has been widely
used in population genetics. However, it has been largely restricted to modeling only a …

Deleterious genetic variation is abundant in wild populations, and understanding the
ecological and conservation implications of such variation is an area of active research …

With the desire to model population genetic processes under increasingly realistic
scenarios, forward genetic simulations have become a critical part of the toolbox of modern …

The observation that small isolated populations often suffer reduced fitness from inbreeding
depression has guided conservation theory and practice for decades. However …

Horse domestication revolutionized warfare and accelerated travel, trade, and the
geographic expansion of languages. Here, we present the largest DNA time series for a non …

Several studies have suggested that introgressed Neandertal DNA was subjected to
negative selection in modern humans. A striking observation in support of this is an apparent …

Population-scale genomic data sets have given researchers incredible amounts of
information from which to infer evolutionary histories. Concomitant with this flood of data …