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Chagas disease: from discovery to a worldwide health problem
Carlos Chagas discovered American trypanosomiasis, also named Chagas disease (CD) in
his honor, just over a century ago. He described the clinical aspects of the disease …
his honor, just over a century ago. He described the clinical aspects of the disease …
Trypanosoma cruzi genetic diversity: Something new for something known about Chagas disease manifestations, serodiagnosis and drug sensitivity
B Zingales - Acta tropica, 2018 - Elsevier
The genetic diversity of Trypanosoma cruzi, the protozoan agent of Chagas disease, is
widely recognized. At present, T. cruzi is partitioned into seven discrete ty** units (DTUs) …
widely recognized. At present, T. cruzi is partitioned into seven discrete ty** units (DTUs) …
Bats as 'special'reservoirs for emerging zoonotic pathogens
The ongoing West African Ebola epidemic highlights a recurring trend in the zoonotic
emergence of virulent pathogens likely to come from bat reservoirs that has caused …
emergence of virulent pathogens likely to come from bat reservoirs that has caused …
1, 3, 4-Thiadiazole: synthesis, reactions, and applications in medicinal, agricultural, and materials chemistry
Y Hu, CY Li, XM Wang, YH Yang, HL Zhu - Chemical reviews, 2014 - ACS Publications
Over the past decades, the bulk of chemists' interests have been on heterocyclic compounds
and their various derivatives as well as their applications in the pharmaceutical and …
and their various derivatives as well as their applications in the pharmaceutical and …
Trypanosoma cruzi transmission in the wild and its most important reservoir hosts in Brazil
Abstract Trypanosoma cruzi (Kinetoplastea: Trypanosomatidae) infects all tissues of its
hosts, which along with humans, include hundreds of mammalian species in the Americas …
hosts, which along with humans, include hundreds of mammalian species in the Americas …
Parasite zoonoses and wildlife: one health, spillover and human activity
RCA Thompson - International journal for parasitology, 2013 - Elsevier
This review examines parasite zoonoses and wildlife in the context of the One Health triad
that encompasses humans, domestic animals, wildlife and the changing ecosystems in …
that encompasses humans, domestic animals, wildlife and the changing ecosystems in …
Trypanosoma cruzi genetic diversity: impact on transmission cycles and Chagas disease
Trypanosoma cruzi, the agent of Chagas disease (ChD), exhibits remarkable biological and
genetic diversity, along with eco-epidemiological complexity. In order to facilitate …
genetic diversity, along with eco-epidemiological complexity. In order to facilitate …
Genetic diversity of Trypanosoma cruzi in bats, and multilocus phylogenetic and phylogeographical analyses supporting Tcbat as an independent DTU (discrete …
Trypanosoma cruzi is a complex of phenotypically and genetically diverse isolates
distributed in six discrete ty** units (DTUs) designated as TcI–TcVI. Five years ago, T …
distributed in six discrete ty** units (DTUs) designated as TcI–TcVI. Five years ago, T …
The history of Chagas disease
D Steverding - Parasites & vectors, 2014 - Springer
The ancestor of Trypanosome cruzi was probably introduced to South American via bats
approximately 7-10 million years ago. When the first humans arrived in the New World, a …
approximately 7-10 million years ago. When the first humans arrived in the New World, a …
Evasion of the Immune Response by Trypanosoma cruzi during Acute Infection
MS Cardoso, JL Reis-Cunha… - Frontiers in …, 2016 - frontiersin.org
Trypanosoma cruzi is the etiologic agent of Chagas disease, a neglected tropical disease
that affects millions of people mainly in Latin America. To establish a life-long infection, T …
that affects millions of people mainly in Latin America. To establish a life-long infection, T …