Age-related macular degeneration
Age-related macular degeneration (AMD) is the leading cause of legal blindness in the
industrialized world. AMD is characterized by accumulation of extracellular deposits, namely …
industrialized world. AMD is characterized by accumulation of extracellular deposits, namely …
The OCT angular sign of Henle fiber layer (HFL) hyperreflectivity (ASHH) and the pathoanatomy of the HFL in macular disease
The Henle fiber layer (HFL) is comprised of bundles of unmyelinated photoreceptor axons
intermingled with outer Müller cell processes. The photoreceptor axons extend from the cell …
intermingled with outer Müller cell processes. The photoreceptor axons extend from the cell …
Towards a better understanding of non-exudative choroidal and macular neovascularization
Non-exudative macular and choroidal neovascularization (MNV and CNV) usually refers to
the entity of treatment-naïve type 1 neovascularization in the absence of associated signs of …
the entity of treatment-naïve type 1 neovascularization in the absence of associated signs of …
Age-related macular degeneration: pathophysiology, management, and future perspectives
Among older adults, age-related macular degeneration (AMD) is a prevalent disabling
condition that begins as subtle visual disturbances and can progress to permanent loss of …
condition that begins as subtle visual disturbances and can progress to permanent loss of …
[HTML][HTML] The effect of pegcetacoplan treatment on photoreceptor maintenance in geographic atrophy monitored by artificial intelligence–based OCT analysis
Purpose To investigate the therapeutic effect of intravitreal pegcetacoplan on the inhibition
of photoreceptor (PR) loss and thinning in geographic atrophy (GA) on conventional spectral …
of photoreceptor (PR) loss and thinning in geographic atrophy (GA) on conventional spectral …
Measuring the contributions of basal laminar deposit and Bruch's membrane in age-related macular degeneration
AA Sura, L Chen, JD Messinger… - … & visual science, 2020 - iovs.arvojournals.org
Purpose: Basal laminar deposit (BLamD) is a consistent finding in age-related macular
degeneration (AMD). We quantified BLamD thickness, appearance, and topography in eyes …
degeneration (AMD). We quantified BLamD thickness, appearance, and topography in eyes …
Significance of hyperreflective foci as an optical coherence tomography biomarker in retinal diseases: characterization and clinical implications
S Fragiotta, S Abdolrahimzadeh… - Journal of …, 2021 - Wiley Online Library
Hyperreflective foci (HRF) is a term coined to depict hyperreflective dots or roundish lesions
within retinal layers visualized through optical coherence tomography (OCT) …
within retinal layers visualized through optical coherence tomography (OCT) …
[HTML][HTML] Hyperreflective foci, optical coherence tomography progression indicators in age-related macular degeneration, include transdifferentiated retinal pigment …
D Cao, B Leong, JD Messinger, D Kar… - … & visual science, 2021 - tvst.arvojournals.org
Purpose: By optical coherence tomography (OCT) imaging, hyperreflective foci (HRF)
indicate progression risk for advanced age-related macular degeneration (AMD) and are in …
indicate progression risk for advanced age-related macular degeneration (AMD) and are in …
[HTML][HTML] Predicting topographic disease progression and treatment response of pegcetacoplan in geographic atrophy quantified by deep learning
Purpose To identify disease activity and effects of intravitreal pegcetacoplan treatment on
the topographic progression of geographic atrophy (GA) secondary to age-related macular …
the topographic progression of geographic atrophy (GA) secondary to age-related macular …
Develo** and validating a multivariable prediction model which predicts progression of intermediate to late age-related macular degeneration—the PINNACLE trial …
Aims Age-related macular degeneration (AMD) is characterised by a progressive loss of
central vision. Intermediate AMD is a risk factor for progression to advanced stages …
central vision. Intermediate AMD is a risk factor for progression to advanced stages …