Contributions of nonhuman primates to research on aging

ES Didier, AG MacLean, M Mohan… - Veterinary …, 2016 - journals.sagepub.com
Aging is the biological process of declining physiologic function associated with increasing
mortality rate during advancing age. Humans and higher nonhuman primates exhibit …

Adult hypothalamic neurogenesis and sleep–wake dysfunction in aging

A Kostin, MA Alam, D McGinty, MN Alam - Sleep, 2021 - academic.oup.com
In the mammalian brain, adult neurogenesis has been extensively studied in the
hippocampal sub-granular zone and the sub-ventricular zone of the anterolateral ventricles …

Survival is reduced when endogenous period deviates from 24 h in a non-human primate, supporting the circadian resonance theory

C Hozer, M Perret, S Pavard, F Pifferi - Scientific Reports, 2020 - nature.com
Circadian rhythms are ubiquitous attributes across living organisms and allow the
coordination of internal biological functions with optimal phases of the environment …

Neuronal Stability, Volumetric Changes, and Decrease in GFAP Expression of Marmoset (Callithrix jacchus) Subcortical Visual Nuclei During Aging

NNM Santana, EHA Silva, SF Santos… - Journal of …, 2024 - Wiley Online Library
The physiological aging process is well known for functional decline in visual abilities.
Among the components of the visual system, the dorsal lateral geniculate nucleus (DLG) …

Thyroxine differentially modulates the peripheral clock: lessons from the human hair follicle

JA Hardman, IS Haslam, N Farjo, B Farjo, R Paus - PLoS One, 2015 - journals.plos.org
The human hair follicle (HF) exhibits peripheral clock activity, with knock-down of clock
genes (BMAL1 and PER1) prolonging active hair growth (anagen) and increasing …

[HTML][HTML] A Standardized Extract of Asparagus officinalis Stem (ETAS®) Ameliorates Cognitive Impairment, Inhibits Amyloid β Deposition via BACE-1 and Normalizes …

YC Chan, CS Wu, TC Wu, YH Lin, SJ Chang - Nutrients, 2019 - mdpi.com
The prevalence of cognitive impairments and circadian disturbances increases in the elderly
and Alzheimer's disease (AD) patients. This study investigated the effects of a standardized …

Gene expression profiling of the SCN in young and old rhesus macaques

DH Eghlidi, SL Luna, DI Brown… - Journal of …, 2018 - jme.bioscientifica.com
In mammals, the suprachiasmatic nucleus (SCN) is the location of a master circadian
pacemaker. It receives photic signals from the environment via the retinal hypothalamic tract …

The Suprachiasmatic Nucleus and the Intergeniculate Leaflet of the Flat-Faced Fruit-Eating Bat (Artibeus planirostris): Retinal Projections and Neurochemical …

NNM Santana, MAS Barros, HHA Medeiros… - Frontiers in …, 2018 - frontiersin.org
In mammals, the suprachiasmatic nucleus (SCN) and the intergeniculate leaflet (IGL) are the
main components of the circadian timing system. The SCN, classically known as the master …

Region-specific glial hyperplasia and neuronal stability of rat lateral geniculate nucleus during aging

FP Fiuza, ACQ Aquino, DA Câmara… - Experimental …, 2017 - Elsevier
The normal aging process is accompanied by functional declines in image-forming and non-
image forming visual systems. Among the components of these systems, the thalamic lateral …

Hypothalamic aging and hormones

ZJ Cai - Vitamins and Hormones, 2021 - Elsevier
It is the heterogeneous changes of hypothalamic functions that determine the chronological
sequence of aging in mammals. Recently, it was hypothesized by Cai the decrease in slow …