Hereditary spastic paraplegias: an update

C Depienne, G Stevanin, A Brice… - Current opinion in …, 2007 - journals.lww.com
Hereditary spastic paraplegias: an update : Current Opinion in Neurology Hereditary spastic
paraplegias: an update : Current Opinion in Neurology Log in or Register Subscribe to …

Janus-faced spatacsin (SPG11): involvement in neurodevelopment and multisystem neurodegeneration

T Pozner, M Regensburger, T Engelhorn, J Winkler… - Brain, 2020 - academic.oup.com
Hereditary spastic paraplegia (HSP) is a heterogeneous group of rare motor neuron
disorders characterized by progressive weakness and spasticity of the lower limbs. HSP …

Mutations in SPG11, encoding spatacsin, are a major cause of spastic paraplegia with thin corpus callosum

G Stevanin, FM Santorelli, H Azzedine, P Coutinho… - Nature …, 2007 - nature.com
Autosomal recessive hereditary spastic paraplegia (ARHSP) with thin corpus callosum
(TCC) is a common and clinically distinct form of familial spastic paraplegia that is linked to …

Mutations in SPG11 are frequent in autosomal recessive spastic paraplegia with thin corpus callosum, cognitive decline and lower motor neuron degeneration

G Stevanin, H Azzedine, P Denora, A Boukhris, M Tazir… - Brain, 2008 - academic.oup.com
Hereditary spastic paraplegias (HSP) are neurodegenerative diseases mainly characterized
by lower limb spasticity associated, in complicated forms, with additional neurological signs …

Identification of the SPG15 gene, encoding spastizin, as a frequent cause of complicated autosomal-recessive spastic paraplegia, including Kjellin syndrome

S Hanein, E Martin, A Boukhris, P Byrne… - The American Journal of …, 2008 - cell.com
Hereditary spastic paraplegias (HSPs) are genetically and phenotypically heterogeneous
disorders. Both" uncomplicated" and" complicated" forms have been described with various …

Long‐term course and mutational spectrum of spatacsin‐linked spastic paraplegia

U Hehr, P Bauer, B Winner, R Schule… - Annals of Neurology …, 2007 - Wiley Online Library
Abstract Objective Hereditary spastic paraplegias (HSPs) comprise a heterogeneous group
of neurodegenerative disorders resulting in progressive spasticity of the lower limbs. One …

Musician's dystonia and comorbid anxiety: two sides of one coin?

L Enders, JT Spector, E Altenmüller… - Movement …, 2011 - Wiley Online Library
Background: Psychological abnormalities, including anxiety, have been observed in patients
with musician's dystonia (MD). It is unclear if these conditions develop prior to MD or if they …

Novel mutations in SPG11 cause hereditary spastic paraplegia associated with early‐onset levodopa‐responsive Parkinsonism

A Guidubaldi, C Piano, FM Santorelli… - Movement …, 2011 - Wiley Online Library
Background: Autosomal recessive hereditary spastic paraplegia with thin corpus callosum is
a neurodegenerative disorder characterized by spastic paraparesis, cognitive impairment …

Hereditary spastic paraplegia

JK Fink - Neurologic clinics, 2002 - neurologic.theclinics.com
Hereditary spastic paraplegia (HSP; also known as familial spastic paraplegia [FSP] and
Strumpell-Lorrain syndrome)[1] is a syndromic designation for inherited disorders in which …

Hereditary spastic paraplegias: identification of a novel SPG57 variant affecting TFG oligomerization and description of HSP subtypes in Sudan

LEO Elsayed, IN Mohammed, AAA Hamed… - European Journal of …, 2017 - nature.com
Hereditary spastic paraplegias (HSP) are the second most common type of motor neuron
disease recognized worldwide. We investigated a total of 25 consanguineous families from …