Principles of nanoparticle formation by flash nanoprecipitation

WS Saad, RK Prud'homme - Nano Today, 2016‏ - Elsevier
Rapid precipitation is an efficient approach for engineering materials at the nanoscale. By
controlling solute nucleation and growth rates in solvent precipitation processes, the size of …

[HTML][HTML] Application of flash nanoprecipitation to fabricate poorly water-soluble drug nanoparticles

J Tao, SF Chow, Y Zheng - Acta pharmaceutica sinica B, 2019‏ - Elsevier
Nanoparticles are considered to be a powerful approach for the delivery of poorly water-
soluble drugs. One of the main challenges is develo** an appropriate method for …

Nanoparticle size distribution quantification from transmission electron microscopy (TEM) of ruthenium tetroxide stained polymeric nanoparticles

BK Wilson, RK Prud'homme - Journal of Colloid and Interface Science, 2021‏ - Elsevier
Abstract Hypothesis Dynamic Light Scattering (DLS) generated particle size distributions
(PSD) of polymer-stabilized nanoparticles are dependent on the optimization parameters …

Liquid antisolvent precipitation and stabilization of nanoparticles of poorly water soluble drugs in aqueous suspensions: Recent developments and future perspective

AA Thorat, SV Dalvi - Chemical Engineering Journal, 2012‏ - Elsevier
The liquid antisolvent (LAS) precipitation process for production of ultra-fine particles has
been widely researched for a last few decades. In LAS process, precipitation of solute is …

Controlling drug nanoparticle formation by rapid precipitation

SM D'Addio, RK Prud'homme - Advanced drug delivery reviews, 2011‏ - Elsevier
Nanoparticles are a drug delivery platform that can enhance the efficacy of active
pharmaceutical ingredients, including poorly-water soluble compounds, ionic drugs …

Pharmaceutical spray freeze drying

S Wanning, R Süverkrüp, A Lamprecht - International journal of …, 2015‏ - Elsevier
Pharmaceutical spray-freeze drying (SFD) includes a heterogeneous set of technologies
with primary applications in apparent solubility enhancement, pulmonary drug delivery …

Can controversial nanotechnology promise drug delivery?

VR Devadasu, V Bhardwaj, MNVR Kumar - Chemical reviews, 2013‏ - ACS Publications
Observing and visualizing objects, with the help of tools, which cannot be seen with the
naked eye, had always raised curiosity among the scientific community and given scientific …

Flash nanoprecipitation: particle structure and stability

KM Pustulka, AR Wohl, HS Lee, AR Michel… - Molecular …, 2013‏ - ACS Publications
Flash nanoprecipitation (FNP) is a process that, through rapid mixing, stabilizes an insoluble
low molecular weight compound in a nanosized, polymer-stabilized delivery vehicle. The …

Flash nanoprecipitation for the encapsulation of hydrophobic and hydrophilic compounds in polymeric nanoparticles

CE Markwalter, RF Pagels, BK Wilson… - Journal of Visualized …, 2019‏ - app.jove.com
The formulation of a therapeutic compound into nanoparticles (NPs) can impart unique
properties. For poorly water-soluble drugs, NP formulations can improve bioavailability and …

Development of highly stabilized curcumin nanoparticles by flash nanoprecipitation and lyophilization

SF Chow, KY Wan, KK Cheng, KW Wong… - European Journal of …, 2015‏ - Elsevier
The influence of critical operating parameters on the Flash Nanoprecipitation (FNP) and
resulting material properties of curcumin (CUR) nanoparticles has been evaluated using a …