Vitamin D, traditionally known as an essential nutrient, is a precursor of a potent steroid
hormone that regulates a broad spectrum of physiological processes. In addition to its …

Vitamin D is not really a vitamin but the precursor to the potent steroid hormone calcitriol,
which has widespread actions throughout the body. Calcitriol regulates numerous cellular …

Vitamin D and its active metabolites are important nutrients for human skeletal health. UV
irradiation of skin converts 7-dehydrocholesterol into vitamin D3, which metabolized in the …

Background: Observational studies suggest that effects of vitamin D may be stronger for
cancer mortality than for incidence. Yet, existing randomised controlled trials (RCTs) of …

Vitamin D, a fat-soluble prohormone, is synthesised in response to sunlight. Vitamin D
requires two metabolic conversions, 25-hydroxylation in the liver and 1a-hydroxylation in the …

Context: There is increasing evidence that Vitamin D (Vit D) and its metabolites, besides
their well-known calcium-related functions, may also exert antiproliferative, pro …

Abstract Background 1, 25 (OH) 2 D 3 is a fat-soluble vitamin, involved in regulating Ca 2+
homeostasis in the body. Its storage in adipose tissue depends on the fat content of the …

Vitamin D can exert anticancer effect beyond bone and calcium metabolism. We aimed to
investigate whether postoperative vitamin D supplementation affects quality of life (QOL) and …

Anti-estrogen and anti-HER2 treatments have been among the first and most successful
examples of targeted therapy for breast cancer (BC). However, the treatment of triple …

Cancer constitutes a group of heterogeneous diseases that share common features. They
involve the existence of altered cellular pathways which result in uncontrolled cell …