Cellular zinc metabolism and zinc signaling: from biological functions to diseases and therapeutic targets

B Chen, P Yu, WN Chan, F **e, Y Zhang… - Signal transduction and …, 2024 - nature.com
Zinc metabolism at the cellular level is critical for many biological processes in the body. A
key observation is the disruption of cellular homeostasis, often coinciding with disease …

Epidemiology of prostate cancer

P Rawla - World journal of oncology, 2019 - pmc.ncbi.nlm.nih.gov
Prostate cancer is the second most frequent cancer diagnosis made in men and the fifth
leading cause of death worldwide. Prostate cancer may be asymptomatic at the early stage …

Metabolic reprogramming in prostate cancer

F Ahmad, MK Cherukuri, PL Choyke - British journal of cancer, 2021 - nature.com
Although low risk localised prostate cancer has an excellent prognosis owing to effective
treatments, such as surgery, radiation, cryosurgery and hormone therapy, metastatic …

Redox-and non-redox-metal-induced formation of free radicals and their role in human disease

M Valko, K Jomova, CJ Rhodes, K Kuča… - Archives of toxicology, 2016 - Springer
Transition metal ions are key elements of various biological processes ranging from oxygen
formation to hypoxia sensing, and therefore, their homeostasis is maintained within strict …

Lipid metabolism in cancer

CR Santos, A Schulze - The FEBS journal, 2012 - Wiley Online Library
Lipids form a diverse group of water‐insoluble molecules that include triacylglycerides,
phosphoglycerides, sterols and sphingolipids. They play several important roles at cellular …

The role of the prostate in male fertility, health and disease

P Verze, T Cai, S Lorenzetti - Nature Reviews Urology, 2016 - nature.com
Ejaculation is a synchronized cascade of events that has the ultimate goal of activating
sperm and enabling them to reach an egg for fertilization. The seminal plasma contains a …

Zinc and human health: an update

CT Chasapis, AC Loutsidou, CA Spiliopoulou… - Archives of …, 2012 - Springer
The importance of micronutrients in health and nutrition is undisputable, and among them,
zinc is an essential element whose significance to health is increasingly appreciated and …

The emerging role of zinc transporters in cellular homeostasis and cancer

E Bafaro, Y Liu, Y Xu, RE Dempski - Signal transduction and targeted …, 2017 - nature.com
Zinc is an essential micronutrient that plays a role in the structural or enzymatic functions of
many cellular proteins. Cellular zinc homeostasis involves the opposing action of two …

Computer-aided detection and diagnosis for prostate cancer based on mono and multi-parametric MRI: a review

G Lemaître, R Martí, J Freixenet, JC Vilanova… - Computers in biology …, 2015 - Elsevier
Prostate cancer is the second most diagnosed cancer of men all over the world. In the last
few decades, new imaging techniques based on Magnetic Resonance Imaging (MRI) have …

Metabolic adaptations in prostate cancer

M Pujana-Vaquerizo, L Bozal-Basterra… - British Journal of …, 2024 - nature.com
Prostate cancer is one of the most commonly diagnosed cancers in men and is a major
cause of cancer-related deaths worldwide. Among the molecular processes that contribute …