In this review glycosidase activated prodrugs that target cancer cells are discussed.
Glycosylated prodrugs undergo enzymatic bioconversion, cleaving the prodrug to release …

Glycosidases are ubiquitous enzymes that catalyze the hydrolysis of glycosidic linkages in
oligosaccharides and glycoconjugates. These enzymes play a vital role in a wide variety of …

Enzyme prodrug therapies (EPTs) have been intensively explored as attractive approaches
to selective activation of systemically administered benign prodrugs by the exogenous …

Targeting cancer cells with high specificity is one of the most essential yet challenging goals
of tumor therapy. Because different surface receptors, transporters, and integrins are …

Signal transduction across biological membranes is among the most important evolutionary
achievements. Herein, for the design of artificial cells, we engineer fully synthetic receptors …

Rational design of self-assembly drug amphiphiles can provide a promising strategy for
constructing nano-prodrug with high drug loading, smart stimuli-responsive drug release …

The treatment of implant‐associated bacterial infections and biofilms is an urgent medical
need and a grand challenge because biofilms protect bacteria from the immune system and …

Supramolecular prodrugs that combine the merits of stimuli-responsiveness and targeting
ability in a controllable manner have shown appealing prospects in disease diagnostics and …

Nanozymes can mimic the activities of diverse enzymes, and this ability finds applications in
analytical sciences and industrial chemistry, as well as in biomedical applications. Among …

Light has been present throughout the history of mankind and even the universe. It is of
great significance to human life, contributing to energy, agriculture, communication, and …