This review describes how computational modeling can be combined with noninvasive gait
measurements to describe and explain muscle and joint function in human locomotion. Five …

Muscle-driven simulations of human and animal motion are widely used to complement
physical experiments for studying movement dynamics. Musculotendon models are an …

Humans walk and run at a range of speeds. While steady locomotion at a given speed
requires no net mechanical work, moving faster does demand both more positive and …

Despite distinct differences between walking and running, the two types of human
locomotion are likely to be controlled by shared pattern-generating networks. However, the …

The lengths and velocities of muscle fibers have a dramatic effect on muscle force
generation. It is unknown, however, whether the lengths and velocities of lower limb muscle …

The purpose of this study was to investigate the influence of walking speed on the amount
and structure of the stride-to-stride fluctuations of the gait cycle. Based on previous findings …

Human locomotion is a fundamental skill that is required for daily living, yet it is not
completely known how human gait is regulated in a manner that seems so effortless. Gait …

Modulating speed over a large range is important in walking, yet understanding how the
neuromotor patterns adapt to the changing energetic demands of different speeds is not well …

Humans walk and run over a wide range of speeds with remarkable efficiency. For steady
locomotion, moving at different speeds requires the muscle–tendon units of the leg to …

The interaction between the muscle fascicle and tendon components of the human soleus
(SO) muscle influences the capacity of the muscle to generate force and mechanical work …