Malaria, the most prevalent mosquito-borne infectious disease worldwide, has accompanied
humanity for millennia and remains an important public health issue despite advances in its …

The clinical manifestations of cerebral malaria (CM) are well correlated with underlying
major pathophysiological events occurring during an acute malaria infection, the most …

Cerebral malaria (CM), the most lethal clinical syndrome of Plasmodium falciparum
infection, mostly affects children under 5 in sub-Saharan Africa. CM is characterized by …

Motivation. Predominant pathway analysis approaches treat pathways as collections of
individual genes and consider all pathway members as equally informative. As a result, at …

Malaria comprises a spectrum of disease syndromes and the immune system is a major
participant in malarial disease. This is particularly true in relation to the immune responses …

It remains challenging to understand why some hosts suffer severe illnesses, while others
are unscathed by the same infection. We fitted a mathematical model to longitudinal …

Objectives Curcumin is a natural plant product with antimalarial activity and
immunomodulatory properties. In this study we aimed to investigate its effects on CD36 …

Malaria is a common and sometimes fatal disease caused by infection with Plasmodium
parasites. Cerebral malaria (CM) is a most severe complication of infection with Plasmodium …

Genetic map** has been widely employed to search for genes linked to phenotypes/traits
of interest. Because of the ease of maintaining rodent malaria parasites in laboratory mice …

Infectious diseases are responsible for over 25% of deaths globally, but many more
individuals are exposed to deadly pathogens. The outcome of infection results from a set of …