Insulin resistance in polycystic ovary syndrome across various tissues: an updated review of pathogenesis, evaluation, and treatment

H Zhao, J Zhang, X Cheng, X Nie, B He - Journal of Ovarian Research, 2023 - Springer
Polycystic ovary syndrome (PCOS) is a common endocrine disorder characterized by
chronic ovulation dysfunction and overabundance of androgens; it affects 6–20% of women …

[HTML][HTML] Controversies in the pathogenesis, diagnosis and treatment of PCOS: focus on insulin resistance, inflammation, and hyperandrogenism

D Armanini, M Boscaro, L Bordin… - International journal of …, 2022 - mdpi.com
Polycystic ovary syndrome (PCOS) is a heterogeneous and extremely common disease with
symptoms that vary with the age of the patient, typically characterized by hyperandrogenism …

Inositol is an effective and safe treatment in polycystic ovary syndrome: a systematic review and meta-analysis of randomized controlled trials

D Greff, AE Juhász, S Váncsa, A Váradi, Z Sipos… - Reproductive Biology …, 2023 - Springer
Background Metformin is the gold standard insulin sensitizer, which is widely used to treat
insulin resistance in polycystic ovary syndrome (PCOS). However, metformin may induce …

Inositol for Polycystic Ovary Syndrome: a systematic review and meta-analysis to inform the 2023 update of the International Evidence-Based PCOS Guidelines

V Fitz, S Graca, S Mahalingaiah, J Liu… - The Journal of …, 2024 - academic.oup.com
Context Insulin resistance is common in women with polycystic ovary syndrome (PCOS).
Inositol may have insulin sensitizing effects; however, its efficacy in the management of …

[HTML][HTML] Role of Vitamins in Pathogenesis and Treatment of Cancers

S Poudineh, M Poudineh, R Roohinezhad, R Khorram… - Kindle, 2023 - preferpub.org
Vitamins with antioxidant characteristics have been shown as potential chemopreventive
agents because of their roles in quenching free radicals and decreasing oxidative damage …

Myo-inositol and D-chiro-inositol as modulators of ovary steroidogenesis: A narrative review

M Bizzarri, N Monti, A Piombarolo, A Angeloni, R Verna - Nutrients, 2023 - mdpi.com
Myo-inositol is a natural polyol, the most abundant among the nine possible structural
isomers available in living organisms. Inositol confers some distinctive traits that allow for a …

Myo-inositol in assisted reproductive technology from bench to bedside

A Etrusco, AS Laganà, V Chiantera… - Trends in Endocrinology …, 2024 - cell.com
Inositols are insulin-sensitizing compounds of promising efficacy in the management of
polycystic ovary syndrome (PCOS). On the one hand, myo-inositol (myo-ins) plays a …

[HTML][HTML] Overview of neural tube defects: gene–environment interactions, preventative approaches and future perspectives

J Isaković, I Šimunić, D Jagečić, V Hribljan, D Mitrečić - Biomedicines, 2022 - mdpi.com
Neural tube defects (NTDs) are the second most common congenital malformations of
humans, characterized by impaired development of the central nervous system. Even …

Effect of gestational diabetes mellitus on lipid profile: A systematic review and meta-analysis

FA Rahnemaei, R Pakzad, A Amirian, I Pakzad… - Open …, 2021 - degruyter.com
Gestational diabetes mellitus (GDM) can have adverse effects on pregnancy. GDM is
associated with changes in the lipid profile of pregnant women. Finding out the early ways to …

Effects of in vitro fermentation of Atractylodes chinensis (DC.) Koidz. polysaccharide on fecal microbiota and metabolites in patients with type 2 diabetes mellitus

X Zhang, Q Ma, L Jia, H He, T Zhang, W Jia… - International Journal of …, 2023 - Elsevier
Abstract Atractylodes chinensis (DC.) Koidz. polysaccharide (AKP) has been shown to have
hypoglycemic activity. In this study, the effects of AKP on fecal microbiota and metabolites in …