tRNA-derived RNA fragments in cancer: current status and future perspectives

M Yu, B Lu, J Zhang, J Ding, P Liu, Y Lu - Journal of Hematology & …, 2020 - Springer
Non-coding RNAs (ncRNAs) have been the focus of many studies over the last few decades,
and their fundamental roles in human diseases have been well established. Transfer RNAs …

Deciphering the tRNA-derived small RNAs: origin, development, and future

B Liu, J Cao, X Wang, C Guo, Y Liu, T Wang - Cell Death & Disease, 2021 - nature.com
Transfer RNA (tRNA)-derived small RNAs (tsRNAs), a novel category of small noncoding
RNAs, are enzymatically cleaved from tRNAs. Previous reports have shed some light on the …

A signature of saliva-derived exosomal small RNAs as predicting biomarker for esophageal carcinoma: a multicenter prospective study

K Li, Y Lin, Y Luo, X **ong, L Wang, K Durante, J Li… - Molecular cancer, 2022 - Springer
Background The tRNA-derived small RNAs (tsRNAs) are produced in a nuclease-
dependent manner in responses to variety of stresses that are common in cancers. We focus …

Small RNA sequencing across diverse biofluids identifies optimal methods for exRNA isolation

S Srinivasan, A Yeri, PS Cheah, A Chung, K Danielson… - Cell, 2019 - cell.com
Poor reproducibility within and across studies arising from lack of knowledge regarding the
performance of extracellular RNA (exRNA) isolation methods has hindered progress in the …

Promising applications of human-derived saliva biomarker testing in clinical diagnostics

M Song, H Bai, P Zhang, X Zhou, B Ying - International Journal of Oral …, 2023 - nature.com
Saliva testing is a vital method for clinical applications, for its noninvasive features, richness
in substances, and the huge amount. Due to its direct anatomical connection with oral …

Determining bacterial and host contributions to the human salivary metabolome

A Gardner, HG Parkes, PW So… - Journal of oral …, 2019 - Taylor & Francis
Background: Salivary metabolomics is rapidly advancing. Aim and methods: To determine
the extent to which salivary metabolites reflects host or microbial metabolic activity whole …

Gly-tRF enhances LCSC-like properties and promotes HCC cells migration by targeting NDFIP2

Y Zhou, J Hu, L Liu, M Yan, Q Zhang, X Song… - Cancer Cell …, 2021 - Springer
Background Accumulating evidence demonstrates that tRFs (tRNA-derived small RNA
fragments) and tiRNAs (tRNA-derived stress-induced RNA), an emerging category of …

Spitting in the wind?—The challenges of RNA sequencing for biomarker discovery from saliva

A Gosch, R Banemann, G Dørum, C Haas… - International journal of …, 2024 - Springer
Forensic trace contextualization, ie, assessing information beyond who deposited a
biological stain, has become an issue of great and steadily growing importance in forensic …

[HTML][HTML] The emerging function and promise of tRNA-Derived small RNAs in cancer

N Yang, R Li, R Liu, S Yang, Y Zhao, W **ong… - Journal of …, 2024 - ncbi.nlm.nih.gov
Fragments derived from tRNA, called tRNA-derived small RNAs (tsRNAs), have attracted
widespread attention in the past decade. tsRNAs are widespread in prokaryotic and …

[HTML][HTML] Multiple regulatory roles of the transfer RNA-derived small RNAs in cancers

Y Zhang, X Gu, Y Li, Y Huang, S Ju - Genes & Diseases, 2024 - Elsevier
With the development of sequencing technology, transfer RNA (tRNA)-derived small RNAs
(tsRNAs) have received extensive attention as a new type of small noncoding RNAs. Based …