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Pathophysiology of atherosclerosis
S Jebari-Benslaiman, U Galicia-García… - International journal of …, 2022 - mdpi.com
Atherosclerosis is the main risk factor for cardiovascular disease (CVD), which is the leading
cause of mortality worldwide. Atherosclerosis is initiated by endothelium activation and …
cause of mortality worldwide. Atherosclerosis is initiated by endothelium activation and …
Anti-atherosclerotic therapies: milestones, challenges, and emerging innovations
Atherosclerosis is the main underlying pathology for many cardiovascular diseases (CVDs),
which are the leading cause of death globally and represent a serious health crisis …
which are the leading cause of death globally and represent a serious health crisis …
Mitochondrial calcium overload is a key determinant in heart failure
Calcium (Ca2+) released from the sarcoplasmic reticulum (SR) is crucial for excitation–
contraction (E–C) coupling. Mitochondria, the major source of energy, in the form of ATP …
contraction (E–C) coupling. Mitochondria, the major source of energy, in the form of ATP …
COVID-19 causes ferroptosis and oxidative stress in human endothelial cells
Oxidative stress and endothelial dysfunction have been shown to play crucial roles in the
pathophysiology of COVID-19 (coronavirus disease 2019). On these grounds, we sought to …
pathophysiology of COVID-19 (coronavirus disease 2019). On these grounds, we sought to …
Diabetes and restenosis
Restenosis, defined as the re-narrowing of an arterial lumen after revascularization,
represents an increasingly important issue in clinical practice. Indeed, as the number of stent …
represents an increasingly important issue in clinical practice. Indeed, as the number of stent …
[HTML][HTML] The “metabolic memory” theory and the early treatment of hyperglycemia in prevention of diabetic complications
Several epidemiological and prospective studies suggest that an early intensive control of
hyperglycaemia is able to decrease the risk of diabetic micro-and macro-vascular …
hyperglycaemia is able to decrease the risk of diabetic micro-and macro-vascular …
Mitochondrial oxidative stress promotes atrial fibrillation
Oxidative stress has been suggested to play a role in the pathogenesis of atrial fibrillation
(AF). Indeed, the prevalence of AF increases with age as does oxidative stress. However …
(AF). Indeed, the prevalence of AF increases with age as does oxidative stress. However …
Empagliflozin improves the MicroRNA signature of endothelial dysfunction in patients with heart failure with preserved ejection fraction and diabetes
Endothelial dysfunction represents a key mechanism underlying heart failure with preserved
ejection fraction (HFpEF), diabetes mellitus (DM), and frailty. However, reliable biomarkers …
ejection fraction (HFpEF), diabetes mellitus (DM), and frailty. However, reliable biomarkers …
Calcium release channel RyR2 regulates insulin release and glucose homeostasis
The type 2 ryanodine receptor (RyR2) is a Ca2+ release channel on the endoplasmic
reticulum (ER) of several types of cells, including cardiomyocytes and pancreatic β cells. In …
reticulum (ER) of several types of cells, including cardiomyocytes and pancreatic β cells. In …
Exosomes generated from iPSC-derivatives: new direction for stem cell therapy in human heart diseases
Cardiovascular disease (CVD) is the leading cause of death in modern society. The adult
heart innately lacks the capacity to repair and regenerate the damaged myocardium from …
heart innately lacks the capacity to repair and regenerate the damaged myocardium from …