The evolutionary origin of orphan genes
Gene evolution has long been thought to be primarily driven by duplication and
rearrangement mechanisms. However, every evolutionary lineage harbours orphan genes …
rearrangement mechanisms. However, every evolutionary lineage harbours orphan genes …
Structural and functional discussion of the tetra-trico-peptide repeat, a protein interaction module
N Zeytuni, R Zarivach - Structure, 2012 - cell.com
Tetra-trico-peptide repeat (TPR) domains are found in numerous proteins, where they serve
as interaction modules and multiprotein complex mediators. TPRs can be found in all …
as interaction modules and multiprotein complex mediators. TPRs can be found in all …
Protein sequence analysis using the MPI bioinformatics toolkit
Abstract The MPI Bioinformatics Toolkit (https://toolkit. tuebingen. mpg. de) provides
interactive access to a wide range of the best‐performing bioinformatics tools and …
interactive access to a wide range of the best‐performing bioinformatics tools and …
A completely reimplemented MPI bioinformatics toolkit with a new HHpred server at its core
L Zimmermann, A Stephens, SZ Nam, D Rau… - Journal of molecular …, 2018 - Elsevier
Abstract The MPI Bioinformatics Toolkit (https://toolkit. tuebingen. mpg. de) is a free, one-stop
web service for protein bioinformatic analysis. It currently offers 34 interconnected external …
web service for protein bioinformatic analysis. It currently offers 34 interconnected external …
Assessing the utility of coevolution-based residue–residue contact predictions in a sequence-and structure-rich era
H Kamisetty, S Ovchinnikov… - Proceedings of the …, 2013 - National Acad Sciences
Recently developed methods have shown considerable promise in predicting residue–
residue contacts in protein 3D structures using evolutionary covariance information …
residue contacts in protein 3D structures using evolutionary covariance information …
The MPI bioinformatics Toolkit as an integrative platform for advanced protein sequence and structure analysis
Abstract The MPI Bioinformatics Toolkit (http://toolkit. tuebingen. mpg. de) is an open,
interactive web service for comprehensive and collaborative protein bioinformatic analysis. It …
interactive web service for comprehensive and collaborative protein bioinformatic analysis. It …
X-Linked TEX11 Mutations, Meiotic Arrest, and Azoospermia in Infertile Men
AN Yatsenko, AP Georgiadis, A Röpke… - … England Journal of …, 2015 - Mass Medical Soc
Background The genetic basis of nonobstructive azoospermia is unknown in the majority of
infertile men. Methods We performed array comparative genomic hybridization testing in …
infertile men. Methods We performed array comparative genomic hybridization testing in …
Coordinated regulation of accessory genetic elements produces cyclic di-nucleotides for V. cholerae virulence
The function of the Vibrio 7 th pandemic island-1 (VSP-1) in cholera pathogenesis has
remained obscure. Utilizing chromatin immunoprecipitation sequencing and RNA …
remained obscure. Utilizing chromatin immunoprecipitation sequencing and RNA …
Solution structure of the YTH domain in complex with N6-methyladenosine RNA: a reader of methylated RNA
N6A methylation is the most abundant RNA modification occurring within messenger RNA.
Impairment of methylase or demethylase functions are associated with severe phenotypes …
Impairment of methylase or demethylase functions are associated with severe phenotypes …
Genome of Acanthamoeba castellanii highlights extensive lateral gene transfer and early evolution of tyrosine kinase signaling
Abstract Background The Amoebozoa constitute one of the primary divisions of eukaryotes,
encompassing taxa of both biomedical and evolutionary importance, yet its genomic …
encompassing taxa of both biomedical and evolutionary importance, yet its genomic …