Objectives Mammographic density is a well-defined risk factor for breast cancer and having
extremely dense breast tissue is associated with a one-to six-fold increased risk of breast …

In 2017, breast cancer became the most commonly diagnosed cancer among women in the
US. After lung cancer, breast cancer is the leading cause of cancer-related mortality in …

The tumour stroma regulates nearly all stages of carcinogenesis. Stromal heterogeneity in
human triple‐negative breast cancers (TNBCs) remains poorly understood, limiting the …

ABSTRACT A recent study from GLOBOCAN disclosed that during 2018 two million women
worldwide had been diagnosed with breast cancer. Currently, mammography, magnetic …

Patients with mammographically dense breast tissue have a greatly increased risk of
develo** breast cancer. Dense breast tissue contains more stromal collagen, which …

Altered microarchitecture of collagen type I is a hallmark of wound healing and cancer that is
commonly attributed to myofibroblasts. However, it remains unknown which effect collagen …

Cells within tissues are continuously exposed to physical forces including hydrostatic
pressure, shear stress, and compression and tension forces. Cells dynamically adapt to …

Variations in percent mammographic density (PMD) reflect variations in the amounts of
collagen and number of epithelial and non-epithelial cells in the breast. Extensive PMD is …

Background Mammographically dense breast tissue is one of the greatest risk factors for
develo** breast carcinoma. Despite the strong clinical correlation, breast density has not …

The notion that cell shape and spreading can regulate cell proliferation has evolved over
several years, but only recently has this been linked to forces from within and upon the cell …