[HTML][HTML] Open PHACTS: semantic interoperability for drug discovery
Open PHACTS is a public–private partnership between academia, publishers, small and
medium sized enterprises and pharmaceutical companies. The goal of the project is to …
medium sized enterprises and pharmaceutical companies. The goal of the project is to …
[HTML][HTML] Metabolomics and systems pharmacology: why and how to model the human metabolic network for drug discovery
Highlights•We now have metabolic network models; the metabolome is represented by their
nodes.•Metabolite levels are sensitive to changes in enzyme activities.•Drugs hitchhike on …
nodes.•Metabolite levels are sensitive to changes in enzyme activities.•Drugs hitchhike on …
Toward interoperable bioscience data
To make full use of research data, the bioscience community needs to adopt technologies
and reward mechanisms that support interoperability and promote the growth of an …
and reward mechanisms that support interoperability and promote the growth of an …
[HTML][HTML] Ontology map** for semantically enabled applications
Highlights•Ontology map** enables data analytics through interoperability and
integration.•Map** between ontologies expands coverage across large domains such as …
integration.•Map** between ontologies expands coverage across large domains such as …
Metadata standard and data exchange specifications to describe, model, and integrate complex and diverse high-throughput screening data from the library of …
UD Vempati, C Chung, C Mader… - Journal of …, 2014 - journals.sagepub.com
The National Institutes of Health Library of Integrated Network-based Cellular Signatures
(LINCS) program is generating extensive multidimensional data sets, including biochemical …
(LINCS) program is generating extensive multidimensional data sets, including biochemical …
The eTOX Data-Sharing Project to Advance in Silico Drug-Induced Toxicity Prediction
M Cases, K Briggs, T Steger-Hartmann… - International journal of …, 2014 - mdpi.com
The high-quality in vivo preclinical safety data produced by the pharmaceutical industry
during drug development, which follows numerous strict guidelines, are mostly not available …
during drug development, which follows numerous strict guidelines, are mostly not available …
Structure-based classification and ontology in chemistry
Background Recent years have seen an explosion in the availability of data in the chemistry
domain. With this information explosion, however, retrieving relevant results from the …
domain. With this information explosion, however, retrieving relevant results from the …
Open phacts: A semantic knowledge infrastructure for public and commercial drug discovery research
L Harland - International Conference on Knowledge Engineering …, 2012 - Springer
Introduction Technology advances in the last decade have led to a “digital revolution” in
biomedical research. Much greater volumes of data can be generated in much less time …
biomedical research. Much greater volumes of data can be generated in much less time …
FAIR: Making data AI-ready
FAIR: Making data AI-ready | DIGITAL.CSIC Skip navigation Logo pequeño DigitalCISC
Producción CSIC Áreas e Institutos Navegar ítems por: Fecha Publicación Autor Título Palabras …
Producción CSIC Áreas e Institutos Navegar ítems por: Fecha Publicación Autor Título Palabras …
[HTML][HTML] Towards virtual knowledge broker services for semantic integration of life science literature and data sources
Research in the life sciences requires ready access to primary data, derived information and
relevant knowledge from a multitude of sources. Integration and interoperability of such …
relevant knowledge from a multitude of sources. Integration and interoperability of such …