Despite being the most prevalent cause of inherited blindness in children, Stargardt disease
is yet to achieve the same clinical trial success as has been achieved for other inherited …

The first discovered vitamin, vitamin A, exists in a range of forms, primarily retinoids and
provitamin carotenoids. The bioactive forms of vitamin A, retinol and retinoic acid, have …

Abstract Prominin 1 (PROM1) is considered a biomarker for cancer stem cells, although its
biological role is unclear. Prominin 2 (PROM2) has also been associated with certain …

Importance ThePROM1gene, commonly associated with cone-rod dystrophies, may have
dominant or recessive phenotypes that influence disease onset and severity. Objective To …

Alternative splicing (AS) is a crucial mechanism contributing to proteomic diversity, which is
highly regulated in tissue-and development-specific patterns. Retinal tissue exhibits one of …

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Background Nigella sativa (N. sativa) exhibits anti-inflammatory, antioxidant, antidiabetic,
antimetastatic and antinociceptive effects and has been used to treat dozens of diseases …

Inherited retinal diseases (IRDs) encompass a variety of disease phenotypes and are known
to display both clinical and genetic heterogeneity. A further complexity is that for several IRD …

Variants in the PROM1 gene are associated with cone (− rod) dystrophy, macular dystrophy,
and other phenotypes. We describe the clinical and genetic characteristics of 10 patients …

The adenomas in Cushing's disease frequently exhibit mutations in exon 14, within a
binding motif for the regulatory protein 14-3-3 located between the catalytic domain (DUB) …