Gene silencing as an adaptive defence against viruses

PM Waterhouse, MB Wang, T Lough - Nature, 2001 - nature.com
Gene silencing was perceived initially as an unpredictable and inconvenient side effect of
introducing transgenes into plants. It now seems that it is the consequence of accidentally …

RNA silencing in plants--defense and counterdefense

V Vance, H Vaucheret - science, 2001 - science.org
RNA silencing is a remarkable type of gene regulation based on sequence-specific targeting
and degradation of RNA. The term encompasses related pathways found in a broad range …

The genetics of RNA silencing

M Tijsterman, RF Ketting… - Annual Review of …, 2002 - annualreviews.org
▪ Abstract Although initially recognized as a handy tool to reduce gene expression, RNA
silencing, triggered by double-stranded RNA molecules, is now recognized as a mechanism …

Tissue-Specific Gene Silencing Mediated by a Naturally Occurring Chalcone Synthase Gene Cluster in Glycine max

JH Tuteja, SJ Clough, WC Chan, LO Vodkin - The Plant Cell, 2004 - academic.oup.com
Chalcone synthase, a key regulatory enzyme in the flavonoid pathway, constitutes an eight-
member gene family in Glycine max (soybean). Three of the chalcone synthase (CHS) gene …

[HTML][HTML] VIP1, an Arabidopsis protein that interacts with Agrobacterium VirE2, is involved in VirE2 nuclear import and Agrobacterium infectivity

T Tzfira, M Vaidya, V Citovsky - The EMBO Journal, 2001 - embopress.org
T‐DNA nuclear import is a central event in genetic transformation of plant cells by
Agrobacterium. This event is thought to be mediated by two bacterial proteins, VirD2 and …

The rest is silence

E Bernstein, AM Denli, GJ Hannon - Rna, 2001 - cambridge.org
The use of double-stranded (ds) RNA to manipulate gene expression is evolving into an
increasingly powerful tool to study gene function in organisms ranging from plants to …

RNA-based silencing strategies in plants

MA Matzke, AJM Matzke, GJ Pruss, VB Vance - Current opinion in genetics …, 2001 - Elsevier
In plants, double-stranded RNA can silence genes by triggering degradation of homologous
RNA in the cytoplasm and by directing methylation of homologous nuclear DNA sequences …

Chalcone synthase as a reporter in virus-induced gene silencing studies of flower senescence

JC Chen, CZ Jiang, T Gookin, D Hunter, D Clark… - Plant molecular …, 2004 - Springer
Agrobacterium-mediated infection of petunia (Petunia hybrida) plants with tobacco rattle
virus (TRV) bearing fragments of Petunia genes resulted in systemic infection and virus …

Specific double-stranded RNA interference in undifferentiated mouse embryonic stem cells

S Yang, S Tutton, E Pierce, K Yoon - Molecular and cellular biology, 2001 - Taylor & Francis
Specific mRNA degradation mediated by double-stranded RNA (dsRNA) interference
(RNAi) is a powerful way of suppressing gene expression in plants, nematodes, and fungal …

A model system for comparative research: Petunia

T Gerats, M Vandenbussche - Trends in plant science, 2005 - cell.com
Research today aims to analyse the development of plant processes over evolutionary time.
To obtain a representative view, a range of plant species covering at least the crucial nodes …