Controlling the sound of light: photoswitching optoacoustic imaging
Optoacoustic (photoacoustic) imaging advances allow high-resolution optical imaging much
deeper than optical microscopy. However, while label-free optoacoustics have already …
deeper than optical microscopy. However, while label-free optoacoustics have already …
Natural photoreceptors as a source of fluorescent proteins, biosensors, and optogenetic tools
Genetically encoded optical tools have revolutionized modern biology by allowing detection
and control of biological processes with exceptional spatiotemporal precision and sensitivity …
and control of biological processes with exceptional spatiotemporal precision and sensitivity …
Bright monomeric near-infrared fluorescent proteins as tags and biosensors for multiscale imaging
Monomeric near-infrared (NIR) fluorescent proteins (FPs) are in high demand as protein
tags and components of biosensors for deep-tissue imaging and multicolour microscopy. We …
tags and components of biosensors for deep-tissue imaging and multicolour microscopy. We …
Signal amplification and transduction in phytochrome photosensors
Sensory proteins must relay structural signals from the sensory site over large distances to
regulatory output domains. Phytochromes are a major family of red-light-sensing kinases …
regulatory output domains. Phytochromes are a major family of red-light-sensing kinases …
The primary structural photoresponse of phytochrome proteins captured by a femtosecond X-ray laser
Phytochrome proteins control the growth, reproduction, and photosynthesis of plants, fungi,
and bacteria. Light is detected by a bilin cofactor, but it remains elusive how this leads to …
and bacteria. Light is detected by a bilin cofactor, but it remains elusive how this leads to …
Protein control of photochemistry and transient intermediates in phytochromes
Phytochromes are ubiquitous photoreceptors responsible for sensing light in plants, fungi
and bacteria. Their photoactivation is initiated by the photoisomerization of the embedded …
and bacteria. Their photoactivation is initiated by the photoisomerization of the embedded …
Near-infrared fluorescent proteins engineered from bacterial phytochromes
Highlights•Available phenotypes and photochemical properties of near-infrared fluorescent
proteins.•Applications of near-infrared fluorescent proteins in basic and translational …
proteins.•Applications of near-infrared fluorescent proteins in basic and translational …
Structural photoactivation of a full-length bacterial phytochrome
Phytochromes are light sensor proteins found in plants, bacteria, and fungi. They function by
converting a photon absorption event into a conformational signal that propagates from the …
converting a photon absorption event into a conformational signal that propagates from the …
How to increase brightness of near-infrared fluorescent proteins in mammalian cells
Numerous near-infrared (NIR) fluorescent proteins (FPs) were recently engineered from
bacterial photoreceptors but lack of their systematic comparison makes researcher's choice …
bacterial photoreceptors but lack of their systematic comparison makes researcher's choice …
On the (un) coupling of the chromophore, tongue interactions, and overall conformation in a bacterial phytochrome
Phytochromes are photoreceptors in plants, fungi, and various microorganisms and cycle
between metastable red light–absorbing (Pr) and far-red light–absorbing (Pfr) states. Their …
between metastable red light–absorbing (Pr) and far-red light–absorbing (Pfr) states. Their …