[HTML][HTML] Mitochondrial DNA heteroplasmy in the emerging field of massively parallel sequencing

RS Just, JA Irwin, W Parson - Forensic Science International: Genetics, 2015 - Elsevier
Long an important and useful tool in forensic genetic investigations, mitochondrial DNA
(mtDNA) ty** continues to mature. Research in the last few years has demonstrated both …

[HTML][HTML] Interpreting NUMTs in forensic genetics: Seeing the forest for the trees

C Marshall, W Parson - Forensic Science International: Genetics, 2021 - Elsevier
Nuclear mitochondrial DNA (mtDNA) segments (NUMTs) were discovered shortly after
sequencing the first human mitochondrial genome. They have earlier been considered to …

The genomic landscape of polymorphic human nuclear mitochondrial insertions

G Dayama, SB Emery, JM Kidd… - Nucleic acids research, 2014 - academic.oup.com
The transfer of mitochondrial genetic material into the nuclear genomes of eukaryotes is a
well-established phenomenon that has been previously limited to the study of static …

[LIBRO][B] Forensic biology: identification and DNA analysis of biological evidence

R Li - 2008 - taylorfrancis.com
Designed as an accessible introduction to basic scientific principles and their application in
professional practice, Forensic Biology provides a concise overview of the field. Focusing …

Massively parallel sequencing of complete mitochondrial genomes from hair shaft samples

W Parson, G Huber, L Moreno, MB Madel… - Forensic Science …, 2015 - Elsevier
Though shed hairs are one of the most commonly encountered evidence types, they are
among the most limited in terms of DNA quantity and quality. As a result, DNA testing has …

[HTML][HTML] Full mtGenome reference data: Development and characterization of 588 forensic-quality haplotypes representing three US populations

RS Just, MK Scheible, SA Fast… - Forensic Science …, 2015 - Elsevier
Though investigations into the use of massively parallel sequencing technologies for the
generation of complete mitochondrial genome (mtGenome) profiles from difficult forensic …

[HTML][HTML] Somatic nuclear mitochondrial DNA insertions are prevalent in the human brain and accumulate over time in fibroblasts

W Zhou, KR Karan, W Gu, HU Klein, G Sturm… - Plos …, 2024 - journals.plos.org
The transfer of mitochondrial DNA into the nuclear genomes of eukaryotes (Numts) has
been linked to lifespan in nonhuman species and recently demonstrated to occur in rare …

Distinguishing mitochondrial DNA and NUMT sequences amplified with the precision ID mtDNA whole genome panel

JC Cihlar, C Strobl, R Lagacé, M Muenzler, W Parson… - Mitochondrion, 2020 - Elsevier
Nuclear mitochondrial DNA segments (NUMTs) are generated via transfer of portions of the
mitochondrial genome into the nuclear genome. Given their common origin, there is the …

Evaluation of mitogenome sequence concordance, heteroplasmy detection, and haplogrou** in a worldwide lineage study using the Precision ID mtDNA Whole …

C Strobl, JC Cihlar, R Lagacé, S Wootton… - Forensic Science …, 2019 - Elsevier
Abstract The emergence of Massively Parallel Sequencing technologies enabled the
analysis of full mitochondrial (mt) DNA sequences from forensically relevant samples that …

Developmental validation of a Nextera XT mitogenome Illumina MiSeq sequencing method for high-quality samples

MA Peck, K Sturk-Andreaggi, JT Thomas… - Forensic science …, 2018 - Elsevier
Generating mitochondrial genome (mitogenome) data from reference samples in a rapid
and efficient manner is critical to harnessing the greater power of discrimination of the entire …