[HTML][HTML] Leishmania infections: Molecular targets and diagnosis

M Akhoundi, T Downing, J Votýpka, K Kuhls… - Molecular aspects of …, 2017 - Elsevier
Progress in the diagnosis of leishmaniases depends on the development of effective
methods and the discovery of suitable biomarkers. We propose firstly an update …

The evolution of trypanosomatid taxonomy

A Kaufer, J Ellis, D Stark, J Barratt - Parasites & vectors, 2017 - Springer
Trypanosomatids are protozoan parasites of the class Kinetoplastida predominately
restricted to invertebrate hosts (ie possess a monoxenous life-cycle). However, several …

Trypanosomatids are much more than just trypanosomes: clues from the expanded family tree

J Lukeš, A Butenko, H Hashimi, DA Maslov… - Trends in …, 2018 - cell.com
Trypanosomes and leishmanias are widely known parasites of humans. However, they are
just two out of several phylogenetic lineages that constitute the family Trypanosomatidae …

Recent advances in trypanosomatid research: genome organization, expression, metabolism, taxonomy and evolution

DA Maslov, FR Opperdoes, AY Kostygov, H Hashimi… - Parasitology, 2019 - cambridge.org
Unicellular flagellates of the family Trypanosomatidae are obligatory parasites of
invertebrates, vertebrates and plants. Dixenous species are aetiological agents of a number …

Ancestral aneuploidy and stable chromosomal duplication resulting in differential genome structure and gene expression control in trypanosomatid parasites

JL Reis-Cunha, SA Pimenta-Carvalho… - Genome …, 2024 - genome.cshlp.org
Aneuploidy is widely observed in both unicellular and multicellular eukaryotes, usually
associated with adaptation to stress conditions. Chromosomal duplication stability is a …

Shining the spotlight on the neglected: new high-quality genome assemblies as a gateway to understanding the evolution of Trypanosomatidae

ATS Albanaz, M Carrington, AO Frolov, AI Ganyukova… - BMC genomics, 2023 - Springer
Background Protists of the family Trypanosomatidae (phylum Euglenozoa) have gained
notoriety as parasites affecting humans, domestic animals, and agricultural plants. However …

Viral discovery and diversity in trypanosomatid protozoa with a focus on relatives of the human parasite Leishmania

D Grybchuk, NS Akopyants, AY Kostygov… - Proceedings of the …, 2018 - pnas.org
Knowledge of viral diversity is expanding greatly, but many lineages remain underexplored.
We surveyed RNA viruses in 52 cultured monoxenous relatives of the human parasite …

TriTrypDB: An integrated functional genomics resource for kinetoplastida

A Shanmugasundram, D Starns, U Böhme… - PLoS neglected …, 2023 - journals.plos.org
Parasitic diseases caused by kinetoplastid parasites are a burden to public health
throughout tropical and subtropical regions of the world. TriTrypDB (https://tritrypdb. org) is a …

Comparative Metabolism of Free‐living Bodo saltans and Parasitic Trypanosomatids

FR Opperdoes, A Butenko, P Flegontov… - Journal of Eukaryotic …, 2016 - Wiley Online Library
Abstract Comparison of the genomes of free‐living Bodo saltans and those of parasitic
trypanosomatids reveals that the transition from a free‐living to a parasitic life style has …

Unwelcome prevalence of leishmaniasis with several other infectious diseases

I Saini, J Joshi, S Kaur - International Immunopharmacology, 2022 - Elsevier
Co-infection among leishmaniasis and other infectious diseases is common among natural
populations especially in the endemic areas of the disease. It depends on the environmental …