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[HTML][HTML] Leishmania infections: Molecular targets and diagnosis
Progress in the diagnosis of leishmaniases depends on the development of effective
methods and the discovery of suitable biomarkers. We propose firstly an update …
methods and the discovery of suitable biomarkers. We propose firstly an update …
The evolution of trypanosomatid taxonomy
Trypanosomatids are protozoan parasites of the class Kinetoplastida predominately
restricted to invertebrate hosts (ie possess a monoxenous life-cycle). However, several …
restricted to invertebrate hosts (ie possess a monoxenous life-cycle). However, several …
Trypanosomatids are much more than just trypanosomes: clues from the expanded family tree
Trypanosomes and leishmanias are widely known parasites of humans. However, they are
just two out of several phylogenetic lineages that constitute the family Trypanosomatidae …
just two out of several phylogenetic lineages that constitute the family Trypanosomatidae …
Recent advances in trypanosomatid research: genome organization, expression, metabolism, taxonomy and evolution
Unicellular flagellates of the family Trypanosomatidae are obligatory parasites of
invertebrates, vertebrates and plants. Dixenous species are aetiological agents of a number …
invertebrates, vertebrates and plants. Dixenous species are aetiological agents of a number …
Ancestral aneuploidy and stable chromosomal duplication resulting in differential genome structure and gene expression control in trypanosomatid parasites
JL Reis-Cunha, SA Pimenta-Carvalho… - Genome …, 2024 - genome.cshlp.org
Aneuploidy is widely observed in both unicellular and multicellular eukaryotes, usually
associated with adaptation to stress conditions. Chromosomal duplication stability is a …
associated with adaptation to stress conditions. Chromosomal duplication stability is a …
Shining the spotlight on the neglected: new high-quality genome assemblies as a gateway to understanding the evolution of Trypanosomatidae
Background Protists of the family Trypanosomatidae (phylum Euglenozoa) have gained
notoriety as parasites affecting humans, domestic animals, and agricultural plants. However …
notoriety as parasites affecting humans, domestic animals, and agricultural plants. However …
Viral discovery and diversity in trypanosomatid protozoa with a focus on relatives of the human parasite Leishmania
Knowledge of viral diversity is expanding greatly, but many lineages remain underexplored.
We surveyed RNA viruses in 52 cultured monoxenous relatives of the human parasite …
We surveyed RNA viruses in 52 cultured monoxenous relatives of the human parasite …
TriTrypDB: An integrated functional genomics resource for kinetoplastida
A Shanmugasundram, D Starns, U Böhme… - PLoS neglected …, 2023 - journals.plos.org
Parasitic diseases caused by kinetoplastid parasites are a burden to public health
throughout tropical and subtropical regions of the world. TriTrypDB (https://tritrypdb. org) is a …
throughout tropical and subtropical regions of the world. TriTrypDB (https://tritrypdb. org) is a …
Comparative Metabolism of Free‐living Bodo saltans and Parasitic Trypanosomatids
Abstract Comparison of the genomes of free‐living Bodo saltans and those of parasitic
trypanosomatids reveals that the transition from a free‐living to a parasitic life style has …
trypanosomatids reveals that the transition from a free‐living to a parasitic life style has …
Unwelcome prevalence of leishmaniasis with several other infectious diseases
Co-infection among leishmaniasis and other infectious diseases is common among natural
populations especially in the endemic areas of the disease. It depends on the environmental …
populations especially in the endemic areas of the disease. It depends on the environmental …