Placebo and Nocebo Effects Placebo and nocebo effects (effects of patients' positive and
negative expectations) are powerful and pervasive in clinical practice. Neurobiologic …

Adverse nocebo responses can cause harm to patients and interfere with treatment
adherence and effects in both clinic practice and clinical trials. Nocebo responses refer to …

Despite their ubiquitous presence, placebos and placebo effects retain an ambiguous and
unsettling presence in biomedicine. Specifically focused on chronic pain, this review …

This randomized controlled trial was performed to investigate whether placebo effects in
chronic low back pain could be harnessed ethically by adding open-label placebo (OLP) …

The high prevalence and societal burden of chronic pain, its undertreatment, and disparities
in its management have contributed to the acknowledgment of chronic pain as a serious …

Modern medicine has progressed in parallel with the advancement of biochemistry,
anatomy, and physiology. By using the tools of modern medicine, the physician today can …

This Perspective reviews recent findings in placebo hypoalgesia and provides a conceptual
account of how expectations and experience can lead to placebo hypoalgesia. In particular …

Information provided to patients is thought to influence placebo and drug effects. In a
prospective, within-subjects, repeated-measures study of 66 subjects with episodic …

Despite its initial treatment as a nuisance variable, the placebo effect is now recognized as a
powerful determinant of health across many different diseases and encounters. This is in …

Today we are witnessing a new science of placebo, a complex discipline that encompasses
several experimental approaches and translational implications. Modern neurobiological …