Cell–extracellular matrix mechanotransduction in 3D

A Saraswathibhatla, D Indana… - Nature Reviews Molecular …, 2023‏ - nature.com
Mechanical properties of extracellular matrices (ECMs) regulate essential cell behaviours,
including differentiation, migration and proliferation, through mechanotransduction. Studies …

Development of scaffolds from bio-based natural materials for tissue regeneration applications: a review

M Krishani, WY Shin, H Suhaimi, NS Sambudi - Gels, 2023‏ - mdpi.com
Tissue damage and organ failure are major problems that many people face worldwide.
Most of them benefit from treatment related to modern technology's tissue regeneration …

[HTML][HTML] Various manufacturing methods and ideal properties of scaffolds for tissue engineering applications

L Suamte, A Tirkey, J Barman, PJ Babu - Smart Materials in Manufacturing, 2023‏ - Elsevier
The precision in the design and manufacturing of scaffolds with ideal properties such as
biocompatibility, biodegradability, mechanical and surface characteristics is very crucial for …

Neuro–bone tissue engineering: emerging mechanisms, potential strategies, and current challenges

W Sun, B Ye, S Chen, L Zeng, H Lu, Y Wan, Q Gao… - Bone research, 2023‏ - nature.com
The skeleton is a highly innervated organ in which nerve fibers interact with various skeletal
cells. Peripheral nerve endings release neurogenic factors and sense skeletal signals …

Cell wall signaling in plant development and defense

S Wolf - Annual Review of Plant Biology, 2022‏ - annualreviews.org
Plant architecture fundamentally differs from that of other multicellular organisms in that
individual cells serve as osmotic bricks, defined by the equilibrium between the internal …

Cellular mechanotransduction: from tension to function

F Martino, AR Perestrelo, V Vinarský, S Pagliari… - Frontiers in …, 2018‏ - frontiersin.org
Living cells are constantly exposed to mechanical stimuli arising from the surrounding
extracellular matrix (ECM) or from neighboring cells. The intracellular molecular processes …

Mechanical forces direct stem cell behaviour in development and regeneration

KH Vining, DJ Mooney - Nature reviews Molecular cell biology, 2017‏ - nature.com
Stem cells and their local microenvironment, or niche, communicate through mechanical
cues to regulate cell fate and cell behaviour and to guide developmental processes. During …

[HTML][HTML] Mechanics in the nervous system: from development to disease

EK Pillai, K Franze - Neuron, 2024‏ - cell.com
Physical forces are ubiquitous in biological processes across scales and diverse contexts.
This review highlights the significance of mechanical forces in nervous system development …

Engineered materials for organoid systems

MJ Kratochvil, AJ Seymour, TL Li, SP Paşca… - Nature Reviews …, 2019‏ - nature.com
Organoids are 3D cell culture systems that mimic some of the structural and functional
characteristics of an organ. Organoid cultures provide the opportunity to study organ-level …

Functional and biomimetic materials for engineering of the three-dimensional cell microenvironment

G Huang, F Li, X Zhao, Y Ma, Y Li, M Lin, G **… - Chemical …, 2017‏ - ACS Publications
The cell microenvironment has emerged as a key determinant of cell behavior and function
in development, physiology, and pathophysiology. The extracellular matrix (ECM) within the …