Semaphorins are membrane-bound or diffusible factors that regulate key cellular functions
and are involved in cell–cell communication. Most of the effects of semaphorins are …

Semaphorin 4D (Sema4D; CD100) is a transmembrane homodimer 150-kDa glycoprotein
member of the Semaphorin family. Semaphorins were first identified as chemorepellants that …

PAX8 is a master transcription factor that is essential during embryogenesis and promotes
neoplastic growth. It is expressed by the secretory cells lining the female reproductive tract …

The success of bioengineered dental pulp depends on two principles,(1) whether the
transplanted tissue can develop its own vascular endothelial tubule network and (2) whether …

The AURELIA trial demonstrated that adding Bevacizumab to chemotherapy significantly
improved progression-free survival (PFS) for platinum resistant recurrent ovarian cancer …

One of the mechanisms by which malignancies can induce immune suppression is through
the production of cytokines that affect the maturation and differentiation of inflammatory cells …

Semaphorins are a group of proteins that are divided into eight subclasses and identified by
a conserved Sema domain on their carboxyl terminus. Sema4A, 4C, and 4D are the …

Over the past few decades, tremendous advances in the prevention, diagnosis, and
treatment of cancer have taken place. However for head and neck cancers, including oral …

The recruitment of mural cells is critical for stabilization of nascent vessels. Stem cells from
human exfoliated deciduous teeth (SHED) are considered to have mural cell-like properties …

Semaphorins constitute a large family of membrane-bound and secreted proteins that
provide guidance cues for axon pathfinding and cell migration. Although initially discovered …