Claudins are tight junction membrane proteins that are expressed in epithelia and
endothelia and form paracellular barriers and pores that determine tight junction …

The functions of Sertoli cells in spermatogenesis have attracted much more attention
recently. Normal spermatogenesis depends on Sertoli cells, mainly due to their influence on …

The blood-testis barrier (BTB) is one of the tightest blood-tissue barriers in the mammalian
body. It divides the seminiferous epithelium into the basal and the apical (adluminal) …

Spermatogenesis is the process by which a single spermatogonium develops into 256
spermatozoa, one of which will fertilize the ovum. Since the 1950s when the stages of the …

Tight junctions (TJs) regulate the passage of ions and molecules through the paracellular
pathway in epithelial and endothelial cells. TJs are highly dynamic structures whose degree …

Epithelial and/or endothelial barriers play a critical role in animal, including human, life
forms. The tight junction (TJ) is an essential component of these barriers. Occludin is a major …

The purpose of this review is to describe the endocrine and local testicular factors that
contribute to the regulation of the blood-testis barrier (BTB), using information gained from in …

Spermatogenesis is an intriguing but complicated biological process. However, many
studies since the 1960s have focused either on the hormonal events of the hypothalamus …

Male infertility caused by exposure to environmental toxicants such as cadmium, mercury,
bisphenol A (BPA) and dioxin is a global problem, particularly in industrialized countries …

Within the mammalian testis, specialized tight junctions between somatic Sertoli cells create
basal and apical polarity within the cells, restrict movement of molecules between cells, and …