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Exosomes in the hypoxic TME: from release, uptake and biofunctions to clinical applications
G He, X Peng, S Wei, S Yang, X Li, M Huang, S Tang… - Molecular Cancer, 2022 - Springer
Hypoxia is a remarkable trait of the tumor microenvironment (TME). When facing selective
pressure, tumor cells show various adaptive characteristics, such as changes in the …
pressure, tumor cells show various adaptive characteristics, such as changes in the …
Mechanisms associated with biogenesis of exosomes in cancer
KM McAndrews, R Kalluri - Molecular cancer, 2019 - Springer
Intercellular communication between cellular compartments within the tumor and at distant
sites is critical for the development and progression of cancer. Exosomes have emerged as …
sites is critical for the development and progression of cancer. Exosomes have emerged as …
Extracellular vesicles and particles impact the systemic landscape of cancer
Intercellular cross talk between cancer cells and stromal and immune cells is essential for
tumor progression and metastasis. Extracellular vesicles and particles (EVPs) are a …
tumor progression and metastasis. Extracellular vesicles and particles (EVPs) are a …
Current knowledge and future perspectives on mesenchymal stem cell-derived exosomes as a new therapeutic agent
Mesenchymal stem cells (MSCs) are on the cusp of regenerative medicine due to their
differentiation capacity, favorable culture conditions, ability to be manipulated in vitro, and …
differentiation capacity, favorable culture conditions, ability to be manipulated in vitro, and …
[HTML][HTML] Scalable production of extracellular vesicles and its therapeutic values: a review
CY Ng, LT Kee, ME Al-Masawa, QH Lee… - International Journal of …, 2022 - mdpi.com
Extracellular vesicles (EVs) are minute vesicles with lipid bilayer membranes. EVs are
secreted by cells for intercellular communication. Recently, EVs have received much …
secreted by cells for intercellular communication. Recently, EVs have received much …
Biogenesis, membrane trafficking, functions, and next generation nanotherapeutics medicine of extracellular vesicles
S Gurunathan, MH Kang, M Qasim… - International Journal of …, 2021 - Taylor & Francis
Extracellular vesicles (EVs) are a heterogeneous group of membrane-limited vesicles and
multi-signal messengers loaded with biomolecules. Exosomes and ectosomes are two …
multi-signal messengers loaded with biomolecules. Exosomes and ectosomes are two …
Emerging function and clinical values of exosomal microRNAs in cancer
M Wang, F Yu, H Ding, Y Wang, P Li, K Wang - Molecular therapy Nucleic …, 2019 - cell.com
Exosomes are a subset of membrane-bound extracellular vesicles with diameters ranging
from 30 to 100 nm. Exosomes enclose a variety of molecules, such as lipids, proteins, and …
from 30 to 100 nm. Exosomes enclose a variety of molecules, such as lipids, proteins, and …
Cardiac cell senescence: molecular mechanisms, key proteins and therapeutic targets
Y Luan, X Zhu, Y Jiao, H Liu, Z Huang, J Pei, Y Xu… - Cell Death …, 2024 - nature.com
Cardiac aging, particularly cardiac cell senescence, is a natural process that occurs as we
age. Heart function gradually declines in old age, leading to continuous heart failure, even in …
age. Heart function gradually declines in old age, leading to continuous heart failure, even in …
Trends in research on exosomes in cancer progression and anticancer therapy
D Sinha, S Roy, P Saha, N Chatterjee, A Bishayee - Cancers, 2021 - mdpi.com
Simple Summary Intensive research in the field of cancer biology has discovered a unique
mode of interplay between cells via extracellular bioactive vesicles called exosomes …
mode of interplay between cells via extracellular bioactive vesicles called exosomes …
The roles of tumor-derived exosomes in non-small cell lung cancer and their clinical implications
H Zheng, Y Zhan, S Liu, J Lu, J Luo, J Feng… - Journal of Experimental & …, 2018 - Springer
Non-small cell lung cancer (NSCLC) accounts for approximately 85% of lung cancer cases,
and it is one of the leading causes of cancer death in both men and women worldwide due …
and it is one of the leading causes of cancer death in both men and women worldwide due …