Over the past few decades, acoustofluidics, one of the branches of microfluidics, has rapidly
developed as a multidisciplinary cutting edge research topic, covering many biomedical and …

A surge of research in intracellular delivery technologies is underway with the increased
innovations in cell‐based therapies and cell reprogramming. Particularly, physical cell …

Protein therapeutics have emerged as a rapidly growing class of medicine in recent years
due to the high potency and specificity. However, protein drugs acting on intracellular targets …

Protein-based therapeutics have unique therapeutic potential due to their specificity,
potency, and low toxicity. The vast majority of intracellular applications of proteins require …

Cytosolic delivery of bioactive agents has exhibited great potential to cure undruggable
targets and diseases. Because biological cell membranes are a natural barrier for living …

Intracellular protein delivery is a transformative tool for biologics research and medicine.
Delivery into the cytosol allows proteins to diffuse throughout the cell and access subcellular …

Rapid and personalized single-cell drug screening testing plays an essential role in acute
myeloid leukemia drug combination chemotherapy. Conventional chemotherapeutic drug …

Cell mechanical motion is a key physiological process that relies on the dynamics of actin
filaments. Herein, a localized shear-force system based on gigahertz acoustic streaming …

Ultrasound-mediated intracellular delivery is one of the popular technologies based on
membrane rupture at present. To date, ultrasound directly acts on a large number of cells to …

Protein therapeutics are of widespread interest due to their successful performance in the
current pharmaceutical and medical fields, even though their broad applications have been …