The complete genomic sequence of Corynebacterium glutamicum ATCC 13032, well-known
in industry for the production of amino acids, eg of l-glutamate and l-lysine was determined …

Methionine is essential in all organisms, as it is both a proteinogenic amino acid and a
component of the cofactor, S-adenosyl methionine. The metabolic pathway for its …

Various high-throughput experimental techniques are routinely used for generating large
amounts of omics data. In parallel, in silico modelling and simulation approaches are being …

The activity of bacteriophages and phage-related mobile elements is a major source for
genome rearrangements and genetic instability of their bacterial hosts. The genome of the …

Amino acids are essential organic compounds in composting products. However, the
mechanism underlying the amino acid metabolism during composting remains unclear. This …

Metabolic pathway analysis was carried out to predict the metabolic potential of
Corynebacterium glutamicum and Escherichia coli for the production of L-methionine. Based …

l-threonine is an essential amino acid for mammals and as such has a wide and expanding
application in industry with a fast growing market demand. The major method of production …

Microorganisms capable of efficient production of amino acids have traditionally been
developed by random mutation and selection method, which might cause unwanted …

The acetyl-CoA “Wood–Ljungdahl” pathway couples the folate-mediated one-carbon (C1)
metabolism to either CO2 reduction or acetate oxidation via acetyl-CoA. This pathway is …

Fermentation processes have been developed for producing most of the essential amino
acids. Methionine is one exception. Although microbial production of methionine has been …