2018 marks the 100-year anniversary of the 1918 influenza pandemic, which killed~ 50
million people worldwide. The severity of this pandemic resulted from a complex interplay …

The 2018–2019 period marks the centennial of the “Spanish” influenza pandemic, which
caused at least 50 million deaths worldwide. The unprecedented nature of the pandemic's …

Neutrophils are immune cells that are well known to be present during many types of lung
diseases associated with acute respiratory distress syndrome (ARDS) and may contribute to …

Just over a century ago in 1918–1919, the “Spanish” influenza pandemic appeared nearly
simultaneously around the world and caused extraordinary mortality—estimated at 50–100 …

Seasonal epidemics caused by antigenic variations in influenza A virus remain a public
health concern and an economic burden. The isolation and characterization of broadly …

The 1918 Spanish influenza pandemic was one of the deadliest infectious disease events in
recorded history, resulting in approximately 50–100 million deaths worldwide. The origins of …

Highly pathogenic influenza A viruses, including avian H5N1 viruses and the 1918
pandemic virus, cause severe respiratory disease in humans and animals. Virus infection is …

The pandemic H1N1 virus of 2009 (2009 H1N1) continues to cause illness worldwide,
primarily in younger age groups. To better understand the pathogenesis of these viruses in …

SARS‐CoV‐2 acute respiratory distress syndrome (ARDS) induces uncontrolled lung
inflammation and coagulopathy with high mortality. Anti‐viral drugs and monoclonal …

Highly pathogenic H5N1 influenza shares the same neuraminidase (NA) subtype with the
2009 pandemic (H1N1pdm09), and cross-reactive NA immunity might protect against or …