Neurotransmitters are released by synaptic vesicle exocytosis at the active zone of a
presynaptic nerve terminal. In this review, I discuss the molecular composition and function …

▪ Abstract Neurotransmitter release is mediated by exocytosis of synaptic vesicles at the
presynaptic active zone of nerve terminals. To support rapid and repeated rounds of release …

In recent years, sensory neuroscientists have made major efforts to dissect the structure and
function of ribbon synapses which process sensory information in the eye and ear. This …

Presynaptic nerve terminals release neurotransmitters by synaptic vesicle exocytosis.
Membrane fusion mediating synaptic exocytosis and other intracellular membrane traffic is …

At a synapse, fast synchronous neurotransmitter release requires localization of Ca 2+
channels to presynaptic active zones. How Ca 2+ channels are recruited to active zones …

Membrane fusion, one of the most fundamental processes in life, occurs when two separate
lipid membranes merge into a single continuous bilayer. Fusion reactions share common …

The physical distance between presynaptic Ca2+ channels and the Ca2+ sensors that
trigger exocytosis of neurotransmitter-containing vesicles is a key determinant of the …

Neurotransmitters are released at presynaptic active zones (AZs). In the fly Drosophila,
monoclonal antibody (MAB) nc82 specifically labels AZs. We employ nc82 to identify …

The molecular organization of presynaptic active zones during calcium influx–triggered
neurotransmitter release is the focus of intense investigation. The Drosophila coiled-coil …

In eukaryotic cells, protein sorting is a highly regulated mechanism important for many
physiological events. After synthesis in the endoplasmic reticulum and trafficking to the Golgi …